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Duovir E Kit Tablet
Salt Composition: EFAVIRENZ,LAMIVUDINE,ZIDOVUDINE
- Manufacturer: CIPLA LTD
- Pack Size: 3 TABLET(s) IN A STRIP
- Dosage Form: TABLET
- Strength: 600MG+150MG+300MG
- Prescription Required
- Storage: Store Duovir E Kit Tablet at (20°C to 25°C). Keep the medicine out of reach of children and pets.
₹117.00₹146.85
Inclusive of all taxes
Product Introduction
Duovir E Kit Tablet contains Efavirenz, Lamivudine, and Zidovudine as active ingredients. It is a combination of three antiretroviral medicines. Lamivudine and Zidovudine are nucleoside/nucleotide reverse transcriptase inhibitors. Efavirenz is a non-nucleoside reverse transcriptase inhibitor. It is used to treat HIV-1 infection, which occurs when a person's immune system is attacked and weakened by the human immunodeficiency virus (HIV). This infection progressively weakens the immune system, making patients more susceptible to opportunistic infections. This drug is contraindicated in patients with severe renal impairment, as this may result in altered drug clearance, which can affect the efficacy and safety of the medicine. Dose adjustment is necessary for such conditions. Inform your doctor if you have any liver disease, including hepatitis B or C, kidney disease, heart problems, diabetes, history of seizures, mental health problems, history of street drug use, or significant alcohol consumption before taking Duovir E Kit Tablet. The administration of this medicine is associated with hematologic toxicity (decrease in blood cells), muscle weakness, liver diseases, infection, and lactic acidosis (acid buildup due to problems in the body's metabolism). Do not breastfeed. During the initial stage of treatment, some patients may experience an inflammatory response to opportunistic infections. This condition, called immune reconstitution syndrome, can occur after starting this drug or other antiretroviral therapies. Monitoring for signs of worsening infections or inflammatory symptoms is necessary. Inform your healthcare provider if symptoms are concerning or persist longer than usual. Patients should report any skin or hypersensitivity reactions to their healthcare provider and seek immediate medical attention if severe reaction symptoms develop. Inform your doctor immediately about all medications you have been taking recently, including herbal products and supplements, before taking Duovir E Kit Tablet.
Uses
HIV-1 Infection
How it works
Duovir E Kit Tablet is a combination of three antiretroviral medicines. It works by inhibiting the enzyme reverse transcriptase, thereby inhibiting the replication of viral particles in the body and treating the infection.
How to Use
Take the Duovir E Kit Tablet as advised by your physician. Swallow the tablets whole and intact. This tablet should be taken with food. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the medicine if your doctor advises you to stop.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Lactic acidosis (breathing difficulties along with weakness in limbs, stomach pain, and drowsiness) Liver problems (yellowing of skin or eyes, tea-colored urine, light-colored stools, abdominal pain) Nervous system symptoms (trouble-concentrating, sleeping, unusual dreams, lack of coordination) Hypersensitive reactions Seizures Changes in body fat Muscle pain or weakness Blood problems (low number of white blood cells) Common Nausea, vomiting Headache, dizziness Tiredness Fever or chills Diarrhea Cough Decreased appetite
Expert Tips
Do not share personal objects such as toothbrushes or razors with anyone. To prevent the spread of HIV infection, avoid sharing needles or syringes, which can transmit the infection easily. It's necessary for individuals who use injectable drugs to use sterile needles and syringes and never share them with others. Personal items should also be avoided. They should not be shared because HIV-1 can be present in blood and certain body fluids, and sharing these items could mainly transmit the virus. Since this drug is unsafe for breastfeeding because HIV infection can be passed to the baby in the breast milk, alternative feeding methods can be followed to nourish the infant's growth. If you forget to take Duovir E Kit Tablet for the entire day, take your usual dose the next day. However, do not double-dose yourself. Throw away medicines that are no longer needed or are out-of-date. Keep medicines away from children and pets. Do not store these medicines in a damp place such as a bathroom, cabinet, or near the kitchen sink.
References
- Strides Arcolab Limited, US Food and Drug Administration, [ Issued on May 2007] [ Accessed on 19th May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/pepfar/022096PI.pdf
- Cipla Ltd, [ Revised on July 2020] [ Accessed on 19th May 2023], https://www.ciplamed.com/content/duovir-e-kit
- KD Tripathi, Essentials of Medical Pharmacology, Antiviral drugs, 7th edition, 2013, 806 - 811.
- Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Antiretroviral agents and treatment of HIV infection, 12th edition, 2011, 1632-1634.
Safety Advice
Pregnancy: unsafe Duovir E Kit Tablet may cause harm to an unborn baby. Inform your doctor if you are pregnant or planning to get pregnant before taking this tablet. The doctor will explain the potential risks and benefits.
Lungs: Consult your doctor It is unknown whether Duovir E Kit Tablet is safe for lung disease patients. Inform your physician if you have any lung diseases before initiating the therapy.
Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Duovir E Kit Tablet because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.