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Ematra Softgel Capsule

Salt Composition: TRETINOIN

₹4500.00₹9466.83

Inclusive of all taxes

Ematra Softgel Capsule

Categories: Dermatology

Conditions: Skin Care

Product Introduction

Ematra Softgel Capsule is an antineoplastic drug containing Tretinoin as its active ingredient. It belongs to the retinoid class of medications, structurally similar to vitamin A. It is indicated for the treatment of acute promyelocytic leukemia, a blood disorder in which it slows the proliferation of diseased blood cells.

Do not take this medicine if you are allergic to Tretinoin or any other component of the formulation. Avoid concurrent use with vitamin A, tetracyclines, or other retinoids (Isotretinoin, Acitretin, Tazarotene).

Avoid consumption of peanuts and soya products, as this medicine contains soya bean oil.

Inform your healthcare professional if you have other medical conditions or a history of mental health problems including depression, mood changes, or aggressive behaviour, as this medicine may affect mood stability.

Before commencing treatment, disclose to your doctor if you are planning pregnancy, are pregnant, or are breastfeeding. Pregnancy must be avoided even for one month after discontinuing this medicine. Use effective contraceptive methods during and after treatment.

Notify your doctor if you have allergies or intolerance to sugars, as this medicine contains sorbitol.

Limited safety and efficacy data are available for paediatric use. Contact your doctor for further guidance.

Report to your doctor immediately if you experience fever, chest or back pain, or difficulty breathing.

Uses

Acute promyelocytic leukemia

How it works

Ematra capsule binds to the fusion protein and breaks down the protein, making the immature blood cells differentiate into mature white blood cells (WBC). This helps restore normal blood cell production and reduces the number of abnormal cells present in blood and bone marrow.

How to Use

Take Ematra capsule as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking Ematra capsule if your doctor advises you to stop.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Difficulty in breathing Fever Coughing Dizziness Pain in chest and abdomen Severe headache Severe stomach pain that spread to back (the sign of pancreatitis) Dark lumpy makings on the skin Swelling in leg Double vision Ringing in the ear and headache Sudden migraine Common Hair loss Irregular heartbeat Joint pain Bone pain Skin rashes, itching, redness, inflammation Dryness in skin, mouth, nose Respiratory failure Unusual sweating Mood swings Numbness or tingling on hands or feet Constipation High levels of blood creatinine or blood fats

Expert Tips

Inform your doctor about the side effect you are experiencing; your doctor may change the dosage of Ematra capsule or give you some additional medicine to reduce the side effects. Even though you didn't notice a change in your mood and, behavior, it is advised you inform your friends and family that this medicine could affect your mood and behavior. Discuss with your doctor about effective contraception methods to avoid getting pregnant. Women should take pregnancy tests every four months while under treatment. Notify your doctor immediately if you become pregnant while under treatment; your doctor will provide you with the right treatment. Do not consume other medications unless your doctor prescribes them.

References

  1. Neon Healthcare Ltd, Electronic Medicines Compendium(EMC), [Revised on Dec 2020], [Accessed on 26th April 2023], Tretinoin 10mg soft capsules - Patient Information Leaflet (PIL) - (emc) (medicines.org.uk)
  2. Glenmark Pharmaceuticals, [Revised on Dec 2018] [Accessed on 26th April 2023], https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=264138c1-9e5f-45ef-be87-79ca97c989d9&type=display
  3. KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.

Safety Advice

Pregnancy: unsafe Ematra capsule is unsafe to use during pregnancy as it may harm the unborn baby. Report to your doctor if you are pregnant or think you may be pregnant or planning for the pregnancy before starting the treatment.

Lungs: Consult your doctor It is unknown whether Ematra capsule is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience difficulty in breathing or any lung-related symptoms.

Breastfeeding: unsafe Taking Ematra capsule while breastfeeding may be unsafe because it may affect the child. Do not breastfeed for at least four months after the treatment. Therefore, talk with your doctor to get more information.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS