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Emgrast M 500mcg Injection
Salt Composition: SARGRAMOSTIM
- Manufacturer: EMCURE PHARMACEUTICALS LTD
- Pack Size: 1 VIAL(s)
- Dosage Form: INJECTION
- Strength: 500MCG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Store Emgrast M 500mcg Injection in the refrigerator (2°C to 8°C) Do not freeze
₹2954.00₹3358.13
Inclusive of all taxes
Product Introduction
Emgrast M 500mcg Injection contains the active ingredient sargramostim. It is an antineoplastic drug belonging to the category of colony-stimulating factors. This medicine is used in the treatment of chemotherapy-induced neutropenia and bone marrow transplantation. It is also found to be useful in treating acute radiation syndrome, which can occur when an individual is exposed to high levels of ionizing radiation over a short period of time. In addition, this medicine is also used to treat peripheral progenitor cell transplantation, a medical procedure used to replace damaged or diseased blood cells.
This drug is contraindicated in patients with known hypersensitivity to any of its components. It should not be used in patients with excessive leukemic myeloid blasts or in patients with known hypersensitivity to yeast-derived products, as this drug is produced in yeast cells. Caution should be taken in patients with underlying medical conditions such as congestive heart failure, pulmonary infiltrates, pulmonary oedema, or renal insufficiency, as these conditions may be exacerbated during therapy.
This medicine has been associated with the development of capillary leak syndrome, a rare disorder that can cause fluid and protein to leak out of blood vessels and into surrounding tissues. Symptoms may include swelling, low blood pressure, or difficulty breathing.
Solutions containing benzyl alcohol, including this injection, should not be administered to neonates and low birth weight infants. This drug is not recommended during pregnancy as it causes harm to the unborn baby. Inform your healthcare provider before beginning this treatment if you are pregnant or planning to conceive.
Uses
Bone Marrow Transplantation Neutropenia caused by chemotherapy Acute Radiation Syndrome Peripheral Progenitor Cell Transplantation
How it works
Emgrast M 500mcg Injection binds to specific receptors on the surface of bone marrow cells, which stimulates the proliferation and differentiation of hematopoietic stem cells. These cells then mature into various types of blood cells, including granulocytes, monocytes, erythrocytes, and platelets. By stimulating the production of these blood cells, this drug can help to prevent or treat certain types of bone marrow failure.
How to Use
Emgrast M 500mcg Injection should only be administered by a trained doctor or nurse experienced in giving chemotherapy. The medicine will be given as a subcutaneous (under the skin) injection, usually once daily. The injection should be given at the same time every day, preferably in the morning. Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity and other factors.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Severe allergic reactions (rash, itching, swelling of lips, tongue, wheezing, dizziness, feeling faint, fast heartbeat, sweating) Fluid retention (swelling of feet or ankles, urinating less than usual, dizziness, sudden weight gain, swelling of the stomach, feeling fullness) Skin flushing along with troubled breathing Abnormal heart rhythm Too high white blood cell count Common Fever Nausea, vomiting Mouth sores Hair loss Weight loss Lung problems Urinary tract problems Diarrhea Headache Rash Abdominal pain High blood pressure Decreased appetite Feeling unwell, lack of energy
Expert Tips
It is important to maintain a healthy and balanced diet to support your overall health and well-being. Eating a variety of nutrient-rich foods such as fruits, vegetables, whole grains, lean protein, and healthy fats can help provide the vitamins and minerals your body needs to support the production of blood cells. Additionally, staying hydrated by drinking plenty of fluids can help support your body's functions.
References
- Sargramostim - Food and Drug Administration. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/103362s5240lbl.pdf (Accessed on April 20, 2023).
- Leukine® (sargramostim). Available at: https://www.leukine.com/ (Accessed on April 20, 2023).
- Bertram.G.Katzung, Basic and Clinical Pharmacology, Drugs Used to Treat Diseases of the Blood, Inflammation, & Gout, 14th edition, 2017, 602.
- Goodman & Gilmanâs, The Pharmacological Basis of Therapeutics, Inflammation, Immunomodulation, Hematopoiesis. 2011,1073-1074.
Safety Advice
Pregnancy: unsafe Emgrast M 500mcg Injection is unsafe to administer in pregnant women because it may fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 6.5 months after your last dose is necessary.
Lungs: Consult your doctor It is unknown whether Emgrast M 500mcg Injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Emgrast M 500mcg Injection because the medicine passes into the breast milk in small amounts and may harm your baby.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.