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Enbrel 25mg Injection

Salt Composition: ETANERCEPT

₹7813.00₹16312.50

Inclusive of all taxes

Enbrel 25mg Injection

Categories: Gastroenterology

Conditions: Arthritis

Product Introduction

Enbrel 25mg Injection contains etanercept as its active component. It is a TNF inhibitor used to treat autoimmune conditions including rheumatoid arthritis, psoriasis, psoriatic arthritis, ankylosing spondylitis, and juvenile idiopathic arthritis. Rheumatoid arthritis is an autoimmune disorder characterised by chronic joint inflammation, resulting in pain, swelling, and potential joint deformity. Psoriatic arthritis is an inflammatory joint condition that occurs in some patients with psoriasis, causing joint pain, stiffness, and swelling. Ankylosing spondylitis is a form of arthritis primarily affecting the spine, causing pain, stiffness, and potential fusion of vertebrae, leading to reduced flexibility. Juvenile idiopathic arthritis comprises a group of chronic arthritic conditions affecting children under 16, causing joint inflammation, pain, and potential joint damage. Biosimilar alternatives to Enbrel 25mg Injection include Etacept, Intacept, Mabura, and Reliance Etanercept. Enbrel 25mg Injection works by suppressing the immune system's overactive response and reducing inflammation, thereby improving symptoms of these chronic inflammatory diseases. While this medication demonstrates efficacy in managing these conditions, potential side effects may include injection site reactions, infections, headaches, and allergic reactions. Enbrel 25mg Injection can be prescribed for paediatric and elderly patients. It is approved for use in children with juvenile idiopathic arthritis and, when appropriately administered, may be beneficial in managing symptoms in older adults with autoimmune diseases. However, cautious monitoring and individualised treatment plans are essential for paediatric and elderly patients to optimise safety and effectiveness. Enbrel 25mg price varies depending on the seller and location.

Uses

Enbrel Injection uses to treat the following: Rheumatoid arthritis Plaque psoriasis Psoriatic arthritis Ankylosing spondylitis Juvenile idiopathic arthritis Non-radiographic axial spondyloarthritis

How it works

Enbrel 25mg Injection's mechanism of action involves its role as a tumor necrosis factor (TNF) inhibitor. By binding to circulating TNF-alpha and acting as a decoy receptor, this medication disrupts the inflammatory signaling pathway, suppressing immune cell activation and reducing the production of inflammatory cytokines. This neutralization of TNF-alpha effectively mitigates inflammation, making it highly effective.

Side Effects

Enbrel side effects, like all medications, may occur in some people, although not everyone will experience them. Serious: Serious infections Tuberculosis (TB) reactivation Hepatitis B reactivation Neurological events Allergic reactions Common: Injection site reactions Upper respiratory infections Headache Nausea

References

  1. KD Tripathi, Essentials of Medical Pharmacology, Anti rheumatoid and Antigout Drugs, 7th edition, 2013,212.
  2. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Dermatological Pharmacology, 12th edition, 2011, 1826.
  3. Pfizer, Electronic medicines compendium (EMC), [Revised on 17 May 2023] [Accessed on 29 July 2023], https://www.medicines.org.uk/emc/product/3837/smpc#gref
  4. Pfizer, US Food and Drug Administration, [Revised on Dec 2017] [Accessed on 29th July 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/103795s5556lbl.pdf

Safety Advice

Pregnancy: Consult your doctor The safety of Enbrel 25mg Injection during pregnancy is not fully established, and its use should be carefully discussed with a healthcare provider, weighing potential risks and benefits for each case.

Lungs: Consult your doctor If you are having any problems related to the lungs, it's essential to inform your healthcare provider about any existing medical conditions before starting Enbrel 25mg Injection treatment.

Breastfeeding: Consult your doctor The safety of Enbrel 25mg Injection during breastfeeding is not fully established. It is recommended to consult with a healthcare provider to assess potential risks and benefits before using the medication while breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS