Endofert H 2mg Tablet

Endofert H 2mg tablet contains estradiol, an active ingredient belonging to vaginal Hormone Replacement Therapy (HRT) medicines. It is classified as an estrogen and possesses properties identical to the naturally occurring estrogen synthesised by women's ovaries. The tablet is indicated for treatment of menopausal symptoms including vaginal atrophy (dryness or irritation of the vagina) in elderly women who have completed menopause.

Do not use Endofert H 2mg tablet if you are allergic to estradiol or its constituents. The tablet is contraindicated in patients with breast cancer or any oestrogen receptor-sensitive cancer. Do not use if you have a clotting disorder, blood clot in veins (lungs or legs), or unexplained vaginal bleeding. The tablet is not advised in patients with history of heart attack, stroke, angina, or abnormal liver function tests. It is not given to patients with porphyria, a rare inherited blood disorder.

Estrogen intake elevates the risk of gallbladder disease. Discontinue estrogen if you experience cholestatic jaundice, severe hypertriglyceridemia, severe hypercalcaemia, or vision loss. Monitoring is advised for women receiving thyroid replacement treatment. Inform your doctor if you have vaginal bleeding, heart, kidney, lung or liver problems, diabetes, asthma, high blood pressure, or hearing disorder. Inform your doctor if you are planning pregnancy, may be pregnant, or are breastfeeding. Discuss your complete medical history with your doctor. Inform your healthcare provider of all medicines you are taking, including herbal, vitamin, and over-the-counter medicines.

Relieve menopausal symptoms of 'vaginal atrophy' (in the vagina such as dryness or irritation) Treatment for hypogonadism, castration, or primary ovarian failure-related hypoestrogenism Preventing osteoporosis after menopause

Endofert H 2mg tablets primarily act by binding to estrogen receptors (ERs) present on the surface of target cells. Upon binding to its receptor, Endofert H 2mg tablets induce a conformational change in the receptor, leading to its activation. Endofert H 2mg tablets replace estrogen (female sex hormone) and prevent the symptoms of menopause, like vaginal irritation or dryness.

Take estradiol tablets exactly as prescribed by your healthcare provider. Do not adjust the dosage or frequency without consulting your doctor. Take your estradiol tablets at the same time each day to maintain a consistent level of hormone in your body. Swallow the estradiol tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this may affect its effectiveness or increase the risk of side effects.

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Common Headache Stomach pain Vaginal bleeding Discharge or discomfort. Serious: Ovarian cancer Blood clots Heart attack Breast lumps Stroke

It is recommended to examine your breast (mammogram) to avoid the risk of breast cancer caused by the drug and inform your doctor if you have any changes in skin color. Always make sure that you have washed your hands before and after the use of the gel. Don't apply it on your breast, eye, or other part of the body apart from the application site. Inform your doctor if you have uterus cancer or a history of blood clots. It is advised to regularly monitor liver function tests, thyroid tests, bone mineral density and blood pressure as treatment with Endofert H 2mg tablets can alter these values.