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Endoxan 50mg Tablet
Salt Composition: CYCLOPHOSPHAMIDE
- Manufacturer: ZYDUS CADILA
- Pack Size: 10 TABLET(s) IN A STRIP
- Dosage Form: TABLET
- Strength: 50MG
- Prescription Required
- Storage: Keep Endoxan 50mg Tablet out of sight and reach of children. Store tablets below or at 25°C. Do not freeze.
₹39.00₹42.60
Inclusive of all taxes
Product Introduction
Endoxan 50mg tablet is a chemotherapy medication containing cyclophosphamide as its active ingredient. It is indicated for treatment of various malignancies including malignant lymphomas such as Hodgkin's disease, lymphocytic lymphoma, and mixed-cell type lymphoma. The tablet is also used in leukemias, neuroblastoma, ovarian cancer, retinoblastoma, and breast carcinoma. Additionally, it is used to treat Minimal Change Nephrotic syndrome in paediatric patients.
Endoxan 50mg tablet is contraindicated in pregnancy, patients with acute infections, urinary tract infections, urinary outflow obstruction, and bone marrow disorders. Treatment with this medicine may result in immune suppression, bone marrow failure, cardiotoxicity, renal toxicity, pulmonary toxicity, and secondary malignancies. Patients with pre-existing kidney disease, immune conditions, cardiac disorders, or liver diseases should inform their doctor before commencing treatment.
Uses
Malignant lymphomas Leukemias Retinoblastoma Carcinoma of breast Ovarian cancer Mycosis fungoides Minimal Change Nephrotic Syndrome in Pediatric Patients
How it works
Endoxan 50mg Tablet slows or stops the growth of cancer cells by damaging the hereditary material (DNA and RNA) of the cancer cells. In nephrotic syndrome, it works by suppressing the bodyâs immune system.
How to Use
Take Endoxan 50mg Table in the dose and duration prescribed by your physician. Swallow the tablets whole and intact. Do not chew or crush the tablets. Avoid exposure to broken tablets; if contact occurs, wash your hands immediately.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious: Infections Immune suppression Blood disorders Allergic reactions Abnormal liver function Inflammation of the bladder Kidney diseases blood in urine sterility impaired wound healing Common: Nausea, vomiting Low white blood cell count Diarrhea Hair loss Fever Weakness Inflammation Dizziness Blurred vision amenorrhea
Expert Tips
Inform the doctor if the patient has any kidney, liver, or heart problems and medication taken for different medical conditions. It causes immune suppression, and hence inform the doctor if there are any immunity-related problems. Endoxan 50mg Tablet should be avoided in pregnant women and breastfeeding mothers. The patient undergoing treatment with this medicine may have dizziness and blurred vision. Consult your doctor before driving and handling heavy machines.
References
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 860.
- Baxter, Electronic medicines compendium (emc), [ Revised on Dec 2016] [ Accessed on 8th April 2021], https://www.medicines.org.uk/emc/product/1813/smpc
- Baxter, US Food and Drug Administration, [ Revised on May 2013] [ Accessed on 7th April 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/012141s090,012142s112lbl.pdf
Safety Advice
Pregnancy: unsafe Endoxan 50mg Tablet may cause fetal harm when administered to a pregnant woman. Inform your physician if you are pregnant or planning to get pregnant before taking this medication. Your physician will instruct you to take it when it is necessary.
Lungs: Consult your doctor It is unknown whether Endoxan 50mg tablet can be given to lung failure patients. Inform your doctor if you have any lung diseases.
Breastfeeding: unsafe Avoid Endoxan 50mg tablet medication if you are breastfeeding. Ask for a doctorâs advice.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.