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Enzalieva 40mg Capsule
Salt Composition: ENZALUTAMIDE
- Manufacturer: Allieva Pharma Pvt. Ltd.
- Pack Size: 28 CAPSULE(s) IN A BOTTLE
- Dosage Form: CAPSULE
- Strength: 40MG
- Prescription Required
- Storage: Enzalieva 40mg Capsule should be stored at room temperature between 20°C and 25°C (68°F and 77°F). It should be kept dry and protected from light and moisture. The capsules should be kept in the original container with the cap tightly closed.. Keep it out of reach from children and pets. It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose.
₹2954.00₹10312.50
Inclusive of all taxes
Product Introduction
Enzalieva 40mg Capsule contains the active compound enzalutamide, which belongs to the class of medications called androgen receptor inhibitors. It is used to treat men with prostate cancer. It is indicated for treatment in men with high testosterone, where prior treatments (hormonal therapy or testosterone-lowering surgery) that reduce testosterone no longer provide adequate disease control. It is also indicated for treatment in metastatic cases where cancer has spread from the prostate to other parts of the body and responds to hormone therapy or surgery to reduce testosterone levels. It is also used for prostate cancer that is responsive to castration (surgical removal of testicles) but is not metastatic, with a high risk of metastasis and biochemical recurrence. Do not take Enzalieva 40mg Capsule if you are allergic to the active compound or any other ingredients in this medicine. It is not recommended for use in children and adolescents below 18 years of age. Men are advised to use effective contraceptive methods during therapy and for 3 months after treatment, as it has the potential to harm a developing foetus. Inform your doctor if you are pregnant or planning to become pregnant to discuss appropriate contraceptive methods. Bone density testing is recommended during treatment. Before starting treatment, inform your physician if you have any infections, kidney, heart, or liver problems. Patients with ischemic heart disease require close monitoring for risk factors. Inform your doctor immediately if you experience seizure, worsening headache, disorientation, blindness, or any other vision problems. It is necessary to inform your physician of all medicines, over-the-counter drugs, vitamins, and herbal supplements you are taking before starting therapy.
Uses
Prostate cancer resistant to other treatments Metastatic prostate cancer reacts to hormone therapy or surgery to reduce testosterone levels Non metastatic prostate cancer with a high chance of spread and recurrence.
How it works
Enzalieva 40mg Capsule medicine acts by blocking the activity of androgens hormone (such as testosterone) by binding with androgen receptors. Enzalieva 40mg Capsule prevents the Androgen receptor from moving to its new site, which further lowers AR-mediated transcriptional activity and stops the growth of tumor cells. Enzalieva 40mg Capsule inhibits the AR complex's ability to bind to DNA, which stops the transcriptional activation of AR target genes. As a result, it reduces testosterone levels and halts the growth and division of prostate cancer cells. Interaction with other drugs:
How to Use
Enzalieva 40mg Capsule is usually taken orally, with or without food. The capsules should be swallowed whole with a glass of water and not crushed, chewed or broken. The dosage and frequency of Enzalieva 40mg Capsule will depend on various factors, including the patient's age, weight, overall health, and the type and stage of cancer being treated. It's important to follow the dosing instructions provided by a healthcare provider, and not to adjust the dosage or frequency without consulting with them first. Pregnant or potentially pregnant women shouldn't handle broken or damaged Xtandi tablets without wearing gloves or other protective gear. If a dose is missed, it should be taken as soon as possible unless it's within 6 hours of the next scheduled dose. In that case, the missed dose should be skipped and the regular dosing schedule resumed. It's important not to take a double dose of abemaciclib to make up for a missed dose.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Tiredness Fall Hot flushes High blood pressure Headache Feeling anxious Dry skin Itching Difficult in remembering Restlessness Serious: Posterior Reversible Encephalopathy Syndrome (PRES) Blockage of the arteries (ischemic heart disease) Enlargement of breast in men (gynaecomastia) Broken bones
Expert Tips
If you have prescribed Enzalieva 40mg Capsule, it is important to follow the instructions provided by your healthcare provider and to report any side effects or concerns promptly. It is advised not to consume grape juice during the treatment. Stay hydrated by consuming lots of liquids, particularly if you get diarrhea when using Enzalieva 40mg Capsule. It's critical to maintain a sufficient fluid intake because dehydration can exacerbate symptoms such as diarrhea and other gastrointestinal disorders. Even if you feel better or see a change in your symptoms, you should still talk to your doctor before stopping Enzalieva 40mg Capsule. It is recommended to monitor your blood counts and bone density at regular intervals. It is not advised for women, particularly for those who are nursing or pregnant. Notify your physician if you experience frequent urges to urinate, blood in your urine, or digestive issues. Inquire with your physician if you get discomfort in the bladder or colon, as the medication may result in bladder or colon cancer as a side effect. Remember to attend all scheduled appointments and follow-up visits with your healthcare provider to ensure your treatment is effective and any side effects are managed appropriately. With proper monitoring and management, Enzalieva 40mg Capsule can be an effective treatment option for prostate cancer.
References
- Astellas Pharma Europe B.V, Electronics Medicines Compendium(emc), [ Revised on December 2022] [ Accessed on 30/03/2024], https://www.medicines.org.uk/emc/files/pil.10318.pdf
- Astellas Pharma US Inc, United States Food and Drug Administration (US FDA), [ Revised on January 2022] [ Accessed on 30/03/2024], https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/203415s018,213674s005lbl.pdf
- Astellas Pharma US, Inc, [Revised on November 2023], [Accessed on 30/03/2024], https://www.astellas.us/docs/12A005-ENZ-WPI.PDF
- KD Tripathi, Essentials of Medical Pharmacology, Adrenergic system and drugs, 7th edition, 2013, 134.
Safety Advice
Pregnancy: unsafe Enzalieva 40mg Capsule is not indicated for use in women. It is unsafe for pregnant women as it may cause foetal harm. It can cause damage to a developing baby if taken during pregnancy. It is important to use effective contraception.
Lungs: Consult your doctor It is unknown whether Enzalieva 40mg Capsule is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Breastfeeding: unsafe Enzalieva 40mg Capsule is not recommended during breastfeeding, as it is unknown if it is excreted in human milk. Because of the potential risk to the infant, breastfeeding is not recommended.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.