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Enzana 80mg Capsule

Salt Composition: ENZALUTAMIDE

₹7260.00₹12100.00

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Enzana 80mg Capsule contains Enzalutamide, a targeted anticancer medicine classified as an androgen receptor inhibitor. It is prescribed in men for advanced prostate cancer, including disease that continues to progress despite hormonal or surgical castration. Prostate cancer growth is often fuelled by male hormones called androgens. Enzana works by blocking the action of these hormones in cancer cells, helping to slow disease progression and improve treatment outcomes. During treatment, your doctor may recommend regular PSA (Prostate-Specific Antigen) tests to monitor response. Routine follow-ups may also include blood pressure monitoring, liver function tests, and complete blood counts, especially in long-term therapy. This medicine may increase the risk of seizures in rare cases, particularly in patients with a history of neurological disorders. Grapefruit and grapefruit juice should be avoided, as they can increase drug levels in the body. Enzana may cause harm to an unborn baby through exposure, so effective contraception is essential for men with female partners of childbearing age during treatment and for at least 3 months after stopping the medicine.

How it works

Enzana 80mg Capsule works by blocking androgen receptors in prostate cancer cells. Normally, androgens (like testosterone and dihydrotestosterone) bind to these receptors and encourage tumour growth. By preventing androgen binding, Enzana : Reduces cancer cell signalling. Slows cancer growth and spread. Lowers tumour activity and progression.

Side Effects

Like most anticancer medicines, Enzana may cause side effects. Not all patients experience them, but awareness helps early management. Common Side Effects Fatigue or tiredness Hot flushes Back pain or joint stiffness High blood pressure Diarrhoea or constipation Headache Reduced appetite Dizziness Dry skin or skin rash Swelling of hands or feet Serious Side Effects Seizures Severe allergic reactions (swelling, breathing difficulty) Posterior Reversible Encephalopathy Syndrome (PRES) Falls and bone fractures Seek urgent medical support if serious symptoms occur.

Expert Tips

Take Enzana at the same time every day for stable drug levels. Avoid grapefruit juice, as it may increase enzalutamide concentration. Monitor blood pressure regularly if you have a history. Stay hydrated and eat balanced meals to reduce weakness and fatigue. Use moisturisers if you develop skin dryness or itching. Inform doctors and dentists that you are on Enzana if planning procedures. Do not stop treatment suddenly without oncologist's advice. Use reliable contraception: barrier protection is recommended during therapy and for 3 months after treatment.

References

  1. Astellas Pharma Ltd, [Revised on Oct 2020] [Accessed on 8th Apr 2021], https://www.astellas.us/docs/12a005-enz-wpi.pdf
  2. Astellas Pharma Europe B.V, Electronic Medicines Compendium (EMC), [Revised on May 2021] [Accessed on 12th Nov 2021], https://www.medicines.org.uk/emc/files/pil.10318.pdf
  3. Martín LázaroQuintela et al., Enzalutamide: a new prostate cancer targeted therapy against the androgen receptor, Cancer Treatment Reviews. Mar 2015; 41(3): 247-253 [Accessed on 8th Apr 2021], https://ruc.udc.es/dspace/bitstream/handle/2183/21551/Lzro_Enzlutamide.pdf?sequence=3&isAllowed=y
  4. Marina D. Kaymakcalan and Christy S. Harris, Prostate Cancer, Applied Therapeutics, The Clinical Use Of Drugs, 11th Edition, 2018, 2083-2100

Safety Advice

Pregnancy: Unsafe Enzana is not used in women, but exposure during pregnancy may cause fetal harm. Men with female partners should use effective contraception during treatment and for 3 months after the final dose.

Lungs: Consult Your Doctor Safety in certain lung conditions has not been fully established. Inform your doctor if you have any chronic breathing issues.

Breastfeeding: Consult Your Doctor Enzana is not intended for use in women, especially during breastfeeding. If accidental exposure occurs, consult a healthcare professional.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS