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Esblocip 2.5gm Injection

Salt Composition: CEFEPIME,ENMETAZOBACTAM

₹1348.00₹1584.37

Inclusive of all taxes

Esblocip 2.5gm Injection

Categories: Infectious Disease

Conditions: Antibacterials

Product Introduction

Esblocip 2.5gm Injection contains Tazobactam and Cefepime. It is indicated for treating bacterial infections including pneumonia (lung infection presenting with fever, cough, and breathing difficulties), urinary tract infections, skin and soft tissue infections, intra-abdominal infections, bone and joint infections, sepsis (life-threatening infection-triggered inflammation), and meningitis (inflammation of brain and spinal cord membranes). The combination is effective against a broad spectrum of bacteria, including both gram-positive and gram-negative organisms.

Patients with known allergy to Tazobactam, Cefepime, or any component of the formulation should not use this medication. Caution is warranted in patients with kidney or liver disease. Patients with a history of seizures or other neurological disorders require careful consideration, as do those taking concomitant medications that may interact, such as warfarin or probenecid. Tazobactam with Cefepime may be used in older adults, although kidney function monitoring and dose adjustment are necessary.

Uses

Esblocip Injection is used for the following: Pneumonia Urinary tract infections (UTIs) Skin and soft tissue infections Intra-abdominal infections Bone and joint infections Sepsis Meningitis

How it works

Esblocip Injection is a combination of two antibiotics. Cefepime is a fourth-generation cephalosporin antibiotic. It works by preventing the bacteria from forming the cell wall that they need to survive. Tazobactum is a beta-lactamase inhibitor. It works by preventing bacteria from breaking down Cefepime.

How to Use

Esblocip 2.5gm Injection is administered intravenously (IV) or intramuscularly (IM) by a healthcare professional. The dose and frequency of administration of this medication will depend on the type and severity of the infection being treated.

Side Effects

Esblocip 2.5gm Injection causes some side effects like all medications, although not everyone will experience them. Serious: Allergic reaction Anaphylaxis Clostridium difficile-associated diarrhea (CDAD) Encephalopathy Neurotoxicity Seizures Common: Diarrhea Nausea Vomiting Rash Itching Pain at the injection site

Expert Tips

Tell your doctor about all the other medications you are taking before starting Esblocip 2.5gm Injection can interact with other medications, such as warfarin, probenecid, and methotrexate. Tell your doctor if you have any allergies, especially to other antibiotics. Tell your doctor if you have any kidney or liver disease. It should be used with caution in people with kidney or liver disease. Tell your doctor if you are pregnant or breastfeeding. It should only be used in pregnancy and breastfeeding if the potential benefits outweigh the risks. Avoid alcohol while using it as it can interact with this medication and increase the risk of side effects. Be careful driving or operating machinery while using it.

References

  1. Sanofi, [Revised on Jun 2018] [Accessed on 3rd Oct 2023], https://www.sanofi.in/-/media/Project/One-Sanofi-Web/Websites/Asia-Pacific/Sanofi-IN/Home/science-and-innovation/for-healthcare-professionals/product-information/Augeoz-API-June-2018.pdf?la=en
  2. Pharmacokinetics-Pharmacodynamics of Tazobactam in Combination with Cefepime in an In Vitro Infection Model, American Society for Microbiology, 2017, 61(12), https://journals.asm.org/doi/epub/10.1128/AAC.01052-17
  3. Biocon Limited, [Accessed on 3rd Oct 2023], http://5.imimg.com/data5/ZN/WV/CF/GLADMIN-59766/celrim-tz-infection-injection-1125-mg-vial.pdf

Safety Advice

Pregnancy: Consult your doctor If you are pregnant or trying to become pregnant, it is important to talk to your doctor before taking Esblocip 2.5gm Injection.

Lungs: Consult your doctor If you have lung diseases, talking to your doctor before taking Esblocip 2.5gm Injection is important.

Breastfeeding: Consult your doctor It is important to talk to your doctor about the risks and benefits before using Esblocip 2.5gm Injection while breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS