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Estiva 600mg Tablet
Salt Composition: EFAVIRENZ
- Manufacturer: HETERO HEALTHCARE LTD
- Pack Size: 30 TABLET(s) IN A BOTTLE
- Dosage Form: TABLET
- Strength: 600MG
- Prescription Required
- Storage: Store at room temperature, between 20°C to 25°C Keep away from moisture, heat, and light. It should not be frozen. Keep away from children and pets.
₹1778.00₹2223.00
Inclusive of all taxes
Product Introduction
Estiva 600mg Tablet contains Efavirenz, a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV (human immunodeficiency virus) infection. It is indicated as part of antiretroviral therapy (ART) in patients with previously treated HIV infection and in those initiating treatment for the first time. The medication is typically administered in combination with other antiretroviral agents, including nucleoside reverse transcriptase inhibitors (NRTIs) or protease inhibitors, to manage HIV infection and reduce the risk of progression to AIDS (acquired immunodeficiency syndrome).
Efavirenz is contraindicated in patients with known hypersensitivity or allergy to Efavirenz or any component of the formulation. The medication is not recommended during pregnancy, particularly in the first trimester, due to potential teratogenic effects on fetal development. Caution is advised in patients with severe hepatic impairment, as Efavirenz is hepatically metabolised and may worsen liver function in this population. Patients with a history of severe psychiatric illness require close monitoring, and alternative treatment options may be considered. Dosage determination in paediatric patients should be individualised based on the child's clinical condition and requirements, with guidance from a healthcare provider. Older adults require careful clinical assessment prior to treatment initiation.
Uses
Estiva 600mg Tablet are used in the following: HIV treatment Antiretroviral therapy (ART) CD4 cell count management Prevention of HIV-related complications Reduction of opportunistic infections Management of drug-resistant HIV strains
How it works
Efavirenz, a non-nucleoside reverse transcriptase inhibitor (NNRTI), operates by inhibiting the enzyme reverse transcriptase, which is essential for the replication of the HIV. Specifically, it binds to the HIV-1 reverse transcriptase enzyme and prevents it from converting RNA into DNA. This action effectively impedes the virus's ability to integrate its genetic material into the DNA of the host cell, thereby inhibiting its replication and reducing the viral load in the body. By hindering the replication of the virus, efavirenz helps to slow down the progression of HIV infection and aids in the preservation of the immune system's function.
How to Use
Estiva 600mg Tablet is primarily administered orally, usually as tablets. It is typically taken orally once daily, with or without food, as directed by a healthcare professional.
Side Effects
Estiva 600mg Tablet causes some side effects like all medications, although not everyone will experience them. Serious Psychiatric symptoms Severe skin reactions Liver problems Common Dizziness Trouble sleeping Drowsiness Abnormal dreams Impaired Concentration or confusion
Expert Tips
Be mindful of any signs of depression, unusual behavior, or mood changes, and inform your healthcare provider if you notice any after taking Estiva 600mg Tablet. Regularly monitor your liver function to ensure the medication is not causing any adverse effects. If you are pregnant or planning to become pregnant, discuss the potential risks and benefits of using this medication with your doctor. Similarly, if you are breastfeeding, consult your healthcare provider to assess the potential risks to the nursing infant. Be cautious about potential interactions with other medications, including over-the-counter drugs and herbal supplements, as they could affect the effectiveness of this medication. Additionally, be aware that it can cause dizziness and vivid dreams, so it's important to be careful when performing tasks that require alertness, such as driving. Always take it as part of combination therapy to prevent the development of drug-resistant strains of HIV, and maintain regular communication with your healthcare provider to ensure the appropriate management of your condition.
References
- EFAVIRENZ-HIGHLIGHTS of PRESCRIBING INFORMATION.; [Revised September 2011] [Accessed 26th Oct 2023]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020972s038lbl.pdf
- Efavirenz 600mg film-coated tablets - Summary of Product Characteristics (SmPC) - (EMC). www.medicines.org.uk. [Published July 2022] [Accessed May 26th Oct 2023] http://www.medicines.org.uk/emc/product/7070/smpc
- KD Tripathi, Essentials of Medical Pharmacology, Antiviral drugs,7th edition, 2013, 809.
- Goodman & Gilmanâs, The Pharmacological Basis of Therapeutics Antiretroviral agents and treatment of HIV infection, 12th edition, 2011, 1643.
Safety Advice
Pregnancy: unsafe Estiva 600mg Tablet is generally unsafe during pregnancy, particularly in the first trimester, due to potential risks to the developing fetus.
Lungs: Consult your doctor Consult your healthcare provider if you have a history of lung conditions before using Estiva 600mg Tablet.
Breastfeeding: Consult your doctor Estiva 600mg Tablet can pass into breast milk and may pose a risk to the nursing infant. Consult your healthcare provider before taking it while breastfeeding.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.