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Etacept 25mg Injection
Salt Composition: ETANERCEPT
- Manufacturer: CIPLA LTD
- Pack Size: 1 PREFILLED SYRINGE
- Dosage Form: INJECTION
- Strength: 25MG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Store at room temperature, between 36°F to 46°F (2°C to 8°C) Keep away from moisture, heat, and light. It should not be frozen. Keep away from children and pets.
₹2625.00₹3281.25
Inclusive of all taxes
Product Introduction
Etacept 25mg Injection contains etanercept, a TNF inhibitor marketed as Enbrel. It is used to treat autoimmune conditions including rheumatoid arthritis, psoriasis, psoriatic arthritis, ankylosing spondylitis, and juvenile idiopathic arthritis.
Rheumatoid arthritis is an autoimmune disorder characterised by chronic joint inflammation, causing pain, swelling, and potential joint deformity. Psoriatic arthritis is an inflammatory joint condition that occurs in some individuals with psoriasis, leading to joint pain, stiffness, and swelling. Ankylosing spondylitis is a form of arthritis primarily affecting the spine, causing pain, stiffness, and potential vertebral fusion with reduced flexibility. Juvenile idiopathic arthritis comprises chronic arthritic conditions affecting children under 16 years, causing joint inflammation, pain, and potential joint damage.
Etacept 25mg Injection suppresses overactive immune response and reduces inflammation, improving symptoms of these chronic inflammatory diseases. Side effects may include injection site reactions, infections, headaches, and allergic reactions.
The injection can be prescribed for paediatric and elderly patients. It is approved for use in children with juvenile idiopathic arthritis and, when appropriately administered, may benefit older adults affected by autoimmune diseases. Cautious monitoring and individualised treatment plans are essential for paediatric and elderly patients to optimise safety and effectiveness.
Uses
Etacept 25mg Injection is used to treat the following: Rheumatoid arthritis Plaque psoriasis Psoriatic arthritis Ankylosing spondylitis Juvenile idiopathic arthritis Non-radiographic axial spondyloarthritis
How it works
Etacept 25mg Injection's mechanism of action involves its role as a tumor necrosis factor (TNF) inhibitor. By binding to circulating TNF-alpha and acting as a decoy receptor, this medication disrupts the inflammatory signaling pathway, suppressing immune cell activation and reducing the production of inflammatory cytokines. This neutralization of TNF-alpha effectively mitigates inflammation, making it highly effective.
How to Use
Etacept 25mg Injection can be administered via subcutaneous injection and intravenous infusion. The choice of administration route depends on the patient's condition, preferences, and the healthcare provider's recommendation, both of which have been proven effective in treating autoimmune diseases.
Side Effects
Etacept 25mg Injection causes some side effects like all medications, although not everyone will experience them. Serious: Serious infections Tuberculosis (TB) reactivation Hepatitis B reactivation Neurological events Allergic reactions Common: Injection site reactions Upper respiratory infections Headache Nausea
Expert Tips
Etacept 25mg Injection increases the risk of serious infections, including tuberculosis and hepatitis B reactivation, and may lead to neurological events. Patients with a history of malignancy, heart failure, autoimmune disorders, or liver impairment should be closely monitored. Live vaccines should be avoided, and non-live vaccines may have reduced efficacy. Use in pregnant and breastfeeding women should be carefully considered. This medication should not be combined with other biological therapies. Close monitoring and prompt reporting of adverse reactions are essential for safe and effective treatment. Patients scheduled for surgery may need to discontinue the drug temporarily. Regular screening and communication with healthcare providers are vital to managing potential risks and optimizing treatment outcomes.
References
- KD Tripathi, Essentials of Medical Pharmacology, Anti rheumatoid and Antigout Drugs, 7th edition, 2013,212.
- Goodman & Gilmanâs, The Pharmacological Basis of Therapeutics, Dermatological Pharmacology, 12th edition, 2011, 1826.
- Pfizer, Electronic medicines compendium (EMC), [Revised on 17 May 2023] [Accessed on 29 July 2023], https://www.medicines.org.uk/emc/product/3837/smpc#gref
- Pfizer, US Food and Drug Administration, [Revised on Dec 2017] [Accessed on 29th July 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/103795s5556lbl.pdf
Safety Advice
Pregnancy: Consult your doctor The safety of Etacept 25mg Injection during pregnancy is not fully established, and its use should be carefully discussed with a healthcare provider, weighing potential risks and benefits for each case.
Lungs: Consult your doctor If you are having any problems related to the lungs, it's essential to inform your healthcare provider about any existing medical conditions before starting Etacept 25mg Injection treatment.
Breastfeeding: Consult your doctor The safety of Etacept 25mg Injection during breastfeeding is not fully established. It is recommended to consult with a healthcare provider to assess potential risks and benefits before using the medication while breastfeeding.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.