EV Active Tablet

EV Active Tablet contains estradiol, a vaginal Hormone Replacement Therapy (HRT) medicine belonging to the estrogen class. Estradiol is identical to the hormone naturally synthesised by women's ovaries. It is indicated for menopausal symptoms including vaginal atrophy (dryness or irritation of the vagina) in elderly women who have completed menopause.

Do not use EV Active Tablet if you are allergic to estradiol or its constituents. It is contraindicated in patients with breast cancer or any oestrogen receptor-sensitive cancer. Do not use if you have a clotting disorder, blood clots in the veins (lungs or legs), or unexplained vaginal bleeding. It is contraindicated in patients with a history of heart attack, stroke, angina, or abnormal liver function tests. EV Active Tablet is not given to patients with porphyria, a rare inherited blood disorder.

Estrogen intake elevates the risk of gallbladder disease. Discontinue estrogen if you experience cholestatic jaundice, severe hypertriglyceridemia, severe hypercalcemia, or vision loss. Caution is advised in women receiving thyroid replacement treatment.

Inform your doctor if you have vaginal bleeding, heart, kidney, lung or liver problems, diabetes, asthma, high blood pressure, or hearing disorder. Inform your doctor if you are planning pregnancy, are pregnant, or are breastfeeding. Discuss your full medical history with your doctor. Inform your healthcare provider of all medicines you are taking, including herbal, vitamin, and over-the-counter medicines.

Relieve menopausal symptoms of 'vaginal atrophy' (in the vagina such as dryness or irritation) Treatment for hypogonadism, castration, or primary ovarian failure-related hypoestrogenism Preventing osteoporosis after menopause

EV Active Tablet primarily acts by binding to estrogen receptors (ERs) present on the surface of target cells upon binding to its receptor, EV Active Tablet induces a conformational change in the receptor, leading to its activation. EV Active Tablet replaces estrogen (female sex hormone) and prevents the symptoms of menopause, like vaginal irritation or dryness.

Take EV Active Tablet exactly as prescribed by your healthcare provider. Do not adjust the dosage or frequency without consulting your doctor. Take your EV Active Tablet at the same time each day to maintain a consistent level of hormones in your body. Swallow the EV Active Tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this may affect its effectiveness or increase the risk of side effects.

Side Effects Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Common Headache Stomach pain Vaginal bleeding Discharge or discomfort. Serious: Ovarian cancer Blood clots Heart attack Breast lumps Stroke

It is recommended to examine your breast (mammogram) to avoid the risk of breast cancer caused by the drug and inform your doctor if you have any changes in skin colour. Don't apply it on your breast, eye, or other part of the body apart from the application site. Inform your doctor if you have uterus cancer or a history of blood clots. Regularly monitoring liver function tests, thyroid tests, bone mineral density, and blood pressure is advised as treatment with EV Active Tablet can alter these values.