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Evenity Injection
Salt Composition: ROMOSOZUMAB
- Manufacturer: AMGEN INC.
- Pack Size: 2 PREFILLED SYRINGE(s)
- Dosage Form: INJECTION
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Store the injection in the refrigerator between 2°C to 8°C. Do not freeze. Keep it out of reach of children.
₹25401.00₹29406.56
Inclusive of all taxes
Product Introduction
Evenity Injection contains romosozumab, a humanised monoclonal antibody that promotes bone formation while simultaneously inhibiting bone resorption. It belongs to the anti-osteoporotic agents class and is indicated for the treatment of osteoporosis in postmenopausal women who are at high risk of fractures. By increasing bone mineral density and strength, Evenity Injection reduces the risk of both vertebral and non-vertebral fractures in patients with severe osteoporosis. This treatment is particularly recommended for patients who have not responded well to other osteoporosis therapies. Evenity Injection is used for reducing the likelihood of fractures in postmenopausal women who have experienced multiple fractures or are at risk due to significantly low bone mass. It is administered as a subcutaneous injection once a month for 12 months. The typical dose is 210 mg per month, provided as two consecutive injections. Patients are usually transitioned to anti-resorptive therapy following completion of the 12-month course to maintain the benefits gained. Although effective, potential side effects include joint pain, headache, injection site reactions, and in rare cases, an increased risk of cardiovascular events. Patients with a history of heart attack or stroke should avoid this medication. Instructions must be followed carefully to minimise potential adverse effects. It is advised to monitor calcium and vitamin D levels during treatment to prevent hypocalcaemia. Calcium and vitamin D levels require monitoring during treatment to prevent hypocalcaemia. The effectiveness of this treatment in improving bone density and reducing fractures has been documented. A healthcare provider should assess individual risks and benefits before initiating treatment, as pricing varies by retailer and location.
Uses
Evenity injection uses Treatment of osteoporosis in postmenopausal women at high risk of fracture Reducing the incidence of vertebral and non-vertebral fractures
How it works
Romosozumab, the active ingredient in Evenity Injection, works by inhibiting sclerostin, a regulatory protein involved in bone metabolism. By blocking sclerostin, Romosozumab leads to increased bone formation and decreased bone resorption, resulting in improved bone mineral density (BMD) and reduced risk of fractures.
Side Effects
Evenity injection side effects: Common: Joint pain Headache Injection site reactions Muscle pain Fatigue Serious but rare side effects: Cardiovascular events such as heart attack or stroke Hypocalcemia (low calcium levels)
References
- https://www.sciencedirect.com/topics/neuroscience/romosozumab
- https://www.ncbi.nlm.nih.gov/books/NBK585139/#:~:text=Romosozumab%20is%20a%20humanized%20monoclonal,formation%20while%20suppressing%20bone%20resorption .
- https://www.ncbi.nlm.nih.gov/books/NBK595381/
Safety Advice
Pregnancy: Consult your doctor Evenity Injection is not indicated for use in pregnant women. Inform your doctor if you are pregnant or planning to become pregnant before starting treatment. The safety of this medication during pregnancy has not been established.
Lungs: Consult your doctor If you have a history of lung conditions such as asthma or chronic obstructive pulmonary disease (COPD), inform your doctor before starting treatment with Evenity Injection. Monitor for symptoms of respiratory infection such as persistent cough or shortness of breath.
Breastfeeding: Consult your doctor Evenity Injection is not indicated to be used in breastfeeding women. Inform your doctor if you are breastfeeding before starting treatment with this medication, as it is unclear whether the drug passes into breast milk and could affect a nursing infant.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.