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Everbliss 5mg Tablet

Salt Composition: EVEROLIMUS

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Everbliss 5mg Tablet

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Everbliss 5mg Tablet is an antineoplastic drug from the mTOR inhibitor class, containing everolimus as its active ingredient. It is indicated for advanced breast cancer, renal cell carcinoma, pancreatic neuroendocrine tumours, and subependymal giant cell astrocytoma (tumours located in the brain ventricles). Maintain good oral hygiene and attend regular dental check-ups during treatment, as this medicine can cause mouth sores or ulcers. For subependymal giant cell astrocytoma, it is often used in combination with cyclophosphamide, an alkylating agent.

This treatment increases the risk of bacterial or viral infections. Patients with a history of Hepatitis B infection face increased chances of reinfection. Report to your healthcare provider if you develop fever, chills, cough, yellowing of skin, joint pain, or swelling during treatment. Limit exposure to sunlight and UV light by wearing protective clothing and applying sunscreen regularly, as this medicine may increase the risk of developing cancers. Do not consume grapefruit juice or grapefruit while taking this medicine.

Everbliss 5mg Tablet is not recommended for children and adolescents under 18 years of age. Seek immediate medical attention if you experience shortness of breath, chest pain, or worsening cough. Your doctor may periodically assess white blood cell counts, platelets, blood sugar, electrolytes, and kidney parameters during treatment to prevent serious complications. This medicine has the potential to cause kidney problems. Inform your doctor before starting treatment if you have been diagnosed with liver disorders, heart failure, high blood cholesterol levels, or hypertension. Avoid live vaccines and close contact with persons who have received live vaccines.

Uses

Advanced breast cancer Advanced renal cell carcinoma Advanced pancreatic neuroendocrine tumours Treatment of subependymal giant cell astrocytoma

How it works

Everbliss 5mg Tablet works by inhibiting the activity of a protein called mammalian target of rapamycin (mTOR), which regulates cell growth. This drug can slow the growth of abnormal cancer cells by blocking the mTOR protein. It mainly helps to reduce the size of tumours and improve outcomes in patients.

How to Use

Your doctor will decide the dose and duration of Everbliss 5mg Tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time everyday, with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water. If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Difficulty breathing, or swallowing Swelling of face, lips, tongue, throat Severe itching, red rash, raised bumps Common Infection (chills, increased temperature) Coughing Wheezing Excessive thirst High urine output or severely decreased urine output Tiredness Bleeding Increased appetite with weight loss

Expert Tips

Everbliss 5mg Tablet have the tendency to cause harm to unborn foetus. Inform your healthcare provider before starting this treatment if you are pregnant, or have a partner who can become pregnant. Your health care provider will conduct a pregnancy test before you start treatment with this drug. Discuss effective birth control methods with your healthcare provider and use them during treatment and for 8 weeks after your last dose. Occurrence of mouth ulcers or sores are pretty common during this treatment, so your healthcare provider will prescribe a mouthwash. Use the mouthwash as recommended which helps prevent and manage the symptoms.

References

  1. Accord Healthcare Limited, Electronic medicines compendium (EMC), [ Revised on Oct 2020] [ Accessed on 18th March 2023], https://www.medicines.org.uk/emc/files/pil.11084.pdf
  2. Jan Hasskarl; Everolimus; Recent Results in Cancer Research; Published on 2018; Accessed on 18/03/2023; https://pubmed.ncbi.nlm.nih.gov/30069763/
  3. Novartis Pharmaceuticals Corporation, US Food and Drug Administration, [ Revised on July 2012] [ Accessed on 18th March 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022334s016lbl.pdf
  4. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Targeted therapy: tyrosine kinase inhibitors, monoclonal antibodies and cytokines, 12th edition, 2011, 1743.
  5. KD Tripathi, Essentials of Medical Pharmacology, Immunosuppressant drugs, 7th edition, 2013, 878 - 882.

Safety Advice

Pregnancy: unsafe Everbliss 5mg Tablet is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Lungs: Consult your doctor Inform your doctor if you have any liver problems before taking Everbliss 5mg Tablet. Regular monitoring of liver function tests is recommended.

Breastfeeding: Consult your doctor It is not known if Everbliss 5mg Tablet passes into your breast milk or if it will affect your baby. Please consult your doctor before breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS