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FEBS 40mg Tablet
Salt Composition: FEBUXOSTAT
- Manufacturer: MEDIART LIFE SCIENCES PVT LTD
- Pack Size: 10 TABLET(s) IN A STRIP
- Dosage Form: TABLET
- Strength: 40MG
- Prescription Required
- Storage: Store FEBS 40mg Tablet in the original package at room temperature (15°C to 30°C). Keep it out of reach from children.
₹81.00₹101.25
Inclusive of all taxes
Product Introduction
FEBS 40mg Tablet is a xanthine oxidase inhibitor containing febuxostat. It is used to treat gout, a form of arthritis caused by excessive accumulation of uric acid in the body, resulting in pain, tenderness, swelling, and difficulty moving the affected joint. Gout can occur in the toe joint, ears, heels, knees, wrists, and fingers. This medication is also used to prevent and treat high blood levels of uric acid, which may occur when patients begin to receive chemotherapy for blood cancers. The drug decreases uric acid levels in the body and is used in the prevention of tumour lysis syndrome (TLS) in patients. TLS is a medical emergency that can occur in patients with certain types of cancer, particularly haematological malignancies such as leukaemia and lymphoma, who are undergoing chemotherapy. TLS can occur when cancer cells break down rapidly, releasing large amounts of intracellular contents such as uric acid, potassium, and phosphate into the bloodstream. During FEBS 40mg Tablet treatment, your doctor may periodically monitor your white blood cell counts, platelets, blood sugar, electrolytes and kidney parameters to prevent serious complications. This medicine has the potential to cause heart problems. Inform your doctor if you have been diagnosed with liver disorders, heart failure, high blood cholesterol levels, or hypertension before starting this treatment. Report to your doctor if you experience any hypersensitive reactions, like itchy skin or rashes, while taking this medicine. This tablet contains lactose as an inactive ingredient, which the body is unable to digest. Lactose is a sugar found in milk and dairy products. It can cause symptoms such as bloating and abdominal pain. If you have lactose intolerance, inform your doctor before starting this therapy.
Uses
Treatment of Gout Treatment of Chemotherapy for blood cancer
How it works
It works by inhibiting the enzyme called xanthine oxidase inhibitors, which is responsible for the production of uric acid in the body. By inhibiting this enzyme, FEBS 40mg Tablet reduces the production of uric acid, which can help prevent gout attacks and the formation of uric acid crystals in the joints and other tissues. FEBS 40mg Tablet reduces the amount of uric acid produced in the body. This can help to lower uric acid levels in the blood and reduce the risk of gout.
How to Use
Your doctor will decide the dose and duration of FEBS 40mg Tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time every day, with or without food. Do not chew, crush, or break the tablet. Swallow the whole tablet with water. If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Diarrhea Headache Rash Nausea Increase in gout symptoms Localised swelling due to retention of fluids in tissues Abnormal liver function Kidney problems
Expert Tips
It is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment. It is not known if FEBS 40mg Tablet passes into the breast milk. Hence, it is not recommended to breastfeed during this treatment. When purines are broken down in the body, they create uric acid, which can contribute to gout,so it is necessary to avoid foods that are high in purines such as (spinach, meat, mushrooms, cauliflower, red meat like beef and pork). Foods that are low in purines, such as fruits, vegetables, and whole grains, are generally safe to eat. It is important to drink plenty of fluids while taking FEBS 40mg Tablet. This can help prevent the formation of kidney stones, which can be a side effect of the medication. Consuming alcohol while taking FEBS 40mg Tablet may increase your risk of developing gout flares. It is recommended to limit your alcohol intake or avoid it altogether while taking FEBS 40mg Tablet.
References
- Accord healthcare limited, Electronic medicines compendium (emc), [Revised on July 2020] [ Accessed on 12th July 2021], https://www.medicines.org.uk/emc/files/pil.10184.pdf
- Takeda Pharmaceuticals America, Inc, US Food and Drug Administration, [Revised on March 2013] [ Accessed on 12th July 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021856s011lbl.pdf
- Takai M;Yamauchi T;Ookura M;Matsuda Y;Tai K;Kishi S;Yoshida A;Iwasaki H;Nakamura T;Ueda T; Febuxostat for management of tumour lysis syndrome including its effects on levels of purine metabolites in patients with haematological malignancies - a single institution's, pharmacokinetic and pilot prospective study, Anticancer research. U.S. National Library of Medicine. Available at: https://pubmed.ncbi.nlm.nih.gov/25503162/ (Accessed on March 25, 2023).
- Takai, M. et al. (2014) Controlling serum uric acid using febuxostat in cancer patients at risk of tumor lysis syndrome, Oncology letters. U.S. National Library of Medicine. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156226/ (Accessed on March 25, 2023).
- Goodman & Gilmanâs, The Pharmacological Basis of Therapeutics, Anti-inflammatory, antipyretic, and analgesic agents; pharmacotherapy of gout, 12th edition, 2011, 1499.
- KD Tripathi, Essentials of Medical Pharmacology, Antirheumatoid and antigout drugs, 7th edition, 2013, 217.
Safety Advice
Pregnancy: Consult your doctor FEBS 40mg Tablet is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Lungs: Consult your doctor It is not known whether FEBS 40mg Tablet can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: unsafe It is not known if FEBS 40mg Tablet tablets pass into your breast milk or if it will affect your baby. Please consult your doctor before breastfeeding.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.