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Fistent 250mg Injection
Salt Composition: FULVESTRANT
- Manufacturer: ADLEY FORMULATIONS
- Pack Size: 1 PREFILLED SYRINGE(s) OF 5ML
- Dosage Form: INJECTION
- Strength: 250MG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Store Fistent 250mg injection in the refrigerator (2°C to 8°C) Do not freeze keep the injection away from the reach of children and pets. If you have missed any dosing appointments, inform your doctor and schedule immediately.
₹9369.00₹17032.50
Inclusive of all taxes
Product Introduction
Fistent 250mg injection contains fulvestrant, an antineoplastic drug and estrogen receptor antagonist. Estrogen, a female sex hormone, can contribute to breast cancer growth. This medicine is used alone to treat postmenopausal women with estrogen receptor-positive breast cancer that is locally advanced or metastatic. It is also indicated in combination with other anticancer medication to treat women with hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer that is locally advanced or metastatic.
Do not use this injection if you are allergic to fulvestrant or any ingredient in this medicine, pregnant, breastfeeding, or have severe liver problems. Before starting treatment, inform your doctor if you have kidney or liver problems, bone disease, bleeding disorders, or heart disease. Fistent 250mg injection is not indicated in children and adolescents under 18 years.
Report to your doctor if you experience allergic reactions, including swelling of the face, lips, tongue, or throat, after administration of this injection.
Common side effects include pain or inflammation at the injection site, abnormal liver enzyme levels, nausea, headache, cough, weakness or tiredness, joint and muscle pain, hot flashes, hair loss, and skin rash.
Your doctor may advise certain blood tests during treatment with this injection. This injection may increase your risk of bleeding and liver failure. Female patients of reproductive potential should use effective contraception during treatment with this injection and for two years after the last dose.
Uses
Treat Hormone receptor (HR)-positive, human epidermal growth receptor 2 (HER2)-negative breast cancer in postmenopausal women.
How it works
Many breast cancers have estrogen receptors (ER), and the growth of these tumors can be stimulated by estrogen. Fistent 250mg injection is an estrogen receptor antagonist that binds to the estrogen receptors in cancer cells and works by blocking the action of estrogen on cancer cells. This can slow or stop the growth of tumor cells.
How to Use
It should only be administered by a trained doctor or nurse as a slow intramuscular injection. Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity and other factors.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Constipation, diarrhea Loss of appetite Nausea, vomiting Decreased RBC, WBC, and Platelets Infections Joint and muscle pain Backache, bone pain Weakness, tiredness Headache Cough, difficulty breathing Hot flushes Pain at the site of injection Serious Changes in heart rhythm Severe neutropenia(decreased WBC) Liver failure, inflammation of liver Hypersensitivity reaction Swelling in the body
Expert Tips
Inform your physician if you have vaginal bleeding, especially at starting of the therapy. This medicine is given as a shot into one of your muscles. Fistent 250mg injection should be used with caution in patients with severe kidney disease. This medicine needs to be given on a fixed schedule; if you miss a dose inform your doctor immediately. Do not breastfeed during treatment and for one year after your last dose. This medicine may cause infertility. Talk to your doctor before using this medicine if you plan to have children.
References
- Faslodex 250 mg solution for injection - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. [2020] [cited 2023 Mar 21]. Available from: https://www.medicines.org.uk/emc/product/68
- HIGHLIGHTS OF PRESCRIBING INFORMATION. [2017] [cited 2023 Mar 21]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021344s034lbl.pdf
- Goodman & Gilmanâs, The Pharmacological Basics of Therapeutics, Estrogens and progestins, 12th edition, 2011, 1177.
Safety Advice
Pregnancy: unsafe Fistent 250mg injection is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 2 years after your last dose is necessary.
Lungs: Consult your doctor It is unknown whether Fistent 250mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Fistent 250mg injection because the medicine passes into the breast milk in small amounts and may harm your baby.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.