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Fluracil 500mg Injection

Salt Composition: FLUOROURACIL

₹17.00₹24.05

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Fluracil 500mg Injection

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Fluracil 500mg Injection contains the active ingredient Fluorouracil. It belongs to the antimetabolites class of drugs, which interfere with DNA and RNA synthesis in rapidly dividing cancer cells, leading to cell death. It is used to treat breast, colorectal, gastric, oesophageal, and pancreatic tumours. It may be administered by injection or as a topical cream. Like all anticancer medications, Fluracil 500mg Injection can cause side effects. Common side effects include nausea, vomiting, diarrhoea, mouth ulcers, hair loss, and increased risk of infection. Not all patients will experience these side effects, and their severity varies between individuals. No specific foods require avoidance during Fluracil 500mg Injection treatment, though alcohol, spicy and acidic foods, citrus fruits and juices, and high-fibre foods may intensify certain side effects such as nausea, vomiting, mouth ulcers, and gastrointestinal disturbances. Patients may consider limiting or avoiding these foods during treatment. Inform your doctor before starting this treatment if you have had surgery within the last 30 days or are following a sodium-restricted diet.

Uses

Fluracil 500mg Injection is used to treat Colon and rectum cancer Breast cancer Gastric cancer Pancreatic cancer Head and Neck cancers Esophagus cancer Anal cancer Bladder cancer

How it works

Fluracil 500mg Injection works by interfering with the DNA and RNA synthesis of rapidly dividing cancer cells, leading to their death. It is an antimetabolite chemotherapy drug that mimics the structure of normal DNA and RNA building blocks. Still, its incorporation into DNA and RNA leads to errors in formation and causes damage to the DNA and RNA strands.

How to Use

Fluracil 500mg Injection is a medication typically administered under a healthcare provider's supervision, usually in a hospital or clinic setting. The method of administration can vary depending on the type of cancer and the individual patient's condition. The injection can be given in a vein (intravenous) or muscle (intramuscular) injection. If a patient misses a scheduled dose, they should contact their healthcare provider immediately to determine the next steps. Sometimes, the missed dose may be rescheduled, or a new treatment plan may be recommended. It is important to follow the healthcare provider's instructions closely and not make any changes to the treatment plan without first consulting with them. Patients should never take a double dose to make up for a missed dose, as this can increase the risk of side effects and toxicity.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Severe chest pain ECG abnormalities Anemia Severe allergic reactions Blood in stool Mouth sores Numbness, tingling, and tremors of hands and feet Rapid heart rate Leukoencephalopathy symptoms Breathlessness Common: Low WBC count, fever Weakness Nausea, vomiting Inflammation in the mouth High uric acid levels in the blood Nosebleeds Muscle pain Hair loss Loss of appetite Watery diarrhea Bone marrow problems Thyroid disorders Infections

Expert Tips

If you have been prescribed Fluracil 500mg Injection for cancer treatment, it is important to take your medication exactly as prescribed by your healthcare provider. It is also important to be aware of the potential side effects of injection, ranging from mild to severe. If you experience any new or worsening symptoms, report them to your healthcare provider immediately. Women of childbearing age should use effective birth control during treatment and afterward, as the injection can harm a developing fetus. If you are pregnant or breastfeeding, discuss the risks and benefits of medication with your healthcare provider. Additionally, patients with liver or kidney disease may require lower doses or more frequent monitoring of liver function during treatment. Regular blood tests and other monitoring tests are required to evaluate the treatment's effectiveness. With careful monitoring and communication, your healthcare provider can help you navigate any challenges or concerns during treatment.

References

  1. Spectrum Pharmaceuticals, Inc., US Food & Drug Administration, U.S. Food and Drug Administration. [Last Revised June 2010] [Accessed April 1, 2023]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/012410s090lbl.pdf
  2. Accord Healthcare Limited, Electronic Medicines Compendium (EMC), [Last Revised], [Accessed 1, April 2023, 2023]. https://www.medicines.org.uk/emc/product/9049/smpc
  3. DeVita, Hellman, and Rosenberg's Cancer: Principles and Practice of Oncology, 11th edition, 2019, 573-582.
  4. Goodman & Gilman's The Pharmacological Basis of Therapeutics, 13th Edition, 2018, 2017, 1317-1322
  5. KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936

Safety Advice

Pregnancy: unsafe Fluracil 500mg Injection is unsafe for pregnant women as it may cause fetal harm. So it is not recommended to take it during pregnancy.

Lungs: Consult your doctor Fluracil 500mg Injection has been associated with some lung-related side effects, although these are relatively uncommon. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: Consult your doctor It is unknown whether it is excreted in human milk or not. So breastfeeding women should discuss with healthcare professionals before the treatment.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS