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Folisurge 1200IU Injection

Salt Composition: FOLLITROPIN ALFA

₹14007.00₹28586.25

Inclusive of all taxes

Categories: Gynaecology

Conditions: Women's Health

Product Introduction

Folisurge 1200IU injection contains follitropin alfa, a synthetic form of follicle-stimulating hormone (FSH). It is used in assisted reproductive technologies (ART) to treat infertility in both men and women. FSH stimulates the development of eggs in females and sperm in males. Infertility refers to the inability to conceive after one year of regular unprotected intercourse.

In women, Folisurge 1200IU injection stimulates the development of multiple follicles. In men, it enhances sperm production. The medication provides precise timing for optimal ovulation and has demonstrated efficacy with a generally safe profile.

Folisurge 1200IU injection is contraindicated in individuals with known hypersensitivity or allergic reaction to follitropin alfa or any of its components. Allergic reactions are rare but possible and require immediate medical attention.

Women with ovarian cysts or tumours should avoid Folisurge 1200IU injection, as it may exacerbate these conditions. Patients with uncontrolled hypothyroidism or adrenal dysfunction should not use this medication. Uncontrolled hypothyroidism refers to a state where thyroid hormone levels remain inadequately regulated, causing persistent symptoms and potential complications.

Individuals with abnormalities or blockages in the reproductive tract that prevent successful egg or sperm transport may not benefit from this medication. Folisurge 1200IU injection is not generally recommended for paediatric or elderly populations.

Uses

Folisurge 1200IU injection is used in the following: Assisted Reproductive Technologies (ART) Ovulation Induction Treatment of Male Infertility Hypogonadism

How it works

Folisurge 1200IU injection, a recombinant follicle-stimulating hormone (FSH), exerts its mechanism of action by binding to the FSH receptors on the ovarian granulosa cells in females or Sertoli cells in males. This binding stimulates the growth and development of ovarian follicles in women, leading to the maturation of eggs, and in men, it promotes the production and maturation of sperm. By mimicking the natural FSH, this medication helps regulate reproductive processes, making it valuable in infertility treatments and other related conditions.

How to Use

Folisurge 1200IU injection is administered through subcutaneous injection. Patients are typically provided with clear instructions and guidance on how to administer the injections safely and effectively during their treatment period.

Side Effects

Folisurge 1200IU injection causes some side effects like all medications, although not everyone will experience them. Serious: Severe Skin ReactionsOvarian Hyperstimulation Syndrome (OHSS) Allergic Reactions Ectopic Pregnancy Blood Clots Common: Injection Site Reactions Abdominal Discomfort Nausea Headache Fatigue

Expert Tips

Patients should be mindful of potential risks of Folisurge 1200IU injection, including Ovarian Hyperstimulation Syndrome (OHSS), multiple pregnancies, and ectopic pregnancy. Women with asthma or respiratory conditions should use it with care, and patients with pre-existing heart conditions should be closely monitored. Fertility treatments can have emotional effects, necessitating adequate psychological support. Patients must inform their healthcare providers of their complete medical history, and proper handling, dosage adjustment, and monitoring are essential. Regular ultrasound examinations and adherence to prescribed dosages are crucial, and patients should be attentive to potential risks and seek counseling and support during treatment. Other considerations include travel precautions, drug disposal, and informed consent to ensure the safest and most effective use of the medication.

References

  1. KD Tripathi, Essentials of Medical Pharmacology, Anterior pituitary hormones, 7th edition, 2013, 241.
  2. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Introduction to Endocrinology: The Hypothalamic-Pituitary Axis, 12th edition, 2011, 1123.
  3. Merck Europe BV, Electronic medicines compendium (EMC), [Revised on 17th Nov 2022] [Accessed on 2nd August 2023], https://www.medicines.org.uk/emc/product/2218/smpc#gref
  4. Serono, US Food and Drug Administration, [Revised on Dec 2020 ] [Accessed on 2nd August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020378s045,s067,s075lbl.pdf

Safety Advice

Pregnancy: unsafe Folisurge 1200IU injection is not recommended for use during pregnancy. If pregnancy occurs during treatment with this medication or any other fertility medications, it is crucial to inform the healthcare provider immediately.

Lungs: Consult your doctor Folisurge 1200IU injection may not have direct adverse effects on the lungs, any medication can potentially cause side effects. It is important to discuss any concerns or existing lung conditions with your healthcare provider before starting this medication.

Breastfeeding: unsafe Folisurge 1200IU injection is not recommended for use during breastfeeding. Before considering its use, consult with a healthcare provider.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS