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Fulvenat 250mg Injection

Salt Composition: FULVESTRANT

₹6704.00₹11465.31

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Fulvenat 250mg injection contains the active substance fulvestrant. It is an antineoplastic drug belonging to the class of estrogen receptor antagonists. Estrogen, a female sex hormone, can sometimes be involved in breast cancer growth. This medicine is used alone to treat postmenopausal women with estrogen receptor-positive breast cancer that is locally advanced or has spread to other parts of the body. It is also indicated in combination with other anticancer medications to treat women with hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer that is locally advanced or has spread to other parts of the body. Do not use this injection if you are allergic to fulvestrant or any other ingredients of this medicine, pregnant or breastfeeding, or have severe liver problems. Before starting treatment, inform your doctor if you have kidney or liver problems, bone diseases, bleeding disorders, or heart diseases. Fulvenat 250mg injection is not indicated in children and adolescents under 18 years of age. Report to your doctor if you experience allergic reactions, including swelling of the face, lips, tongue, or throat, following this injection. Common side effects of Fulvenat 250mg injection include pain or inflammation at the injection site, abnormal liver enzyme levels, nausea, headache, cough, weakness or tiredness, joint and muscle pain, hot flashes, hair loss, and skin rash. Your doctor may recommend certain blood tests while you receive this injection. This injection may increase your risk of bleeding and liver failure. Female patients of reproductive potential should use effective contraception during treatment with this injection and for two years after the final dose.

Uses

Treat Hormone receptor (HR)-positive, human epidermal growth receptor 2 (HER2)-negative breast cancer in postmenopausal women.

How it works

Many breast cancers have estrogen receptors (ER), and the growth of these tumors can be stimulated by estrogen. Fulvenat 250mg injection is an estrogen receptor antagonist that binds to the estrogen receptors in cancer cells and works by blocking the action of estrogen on cancer cells. This can slow or stop the growth of tumor cells.

How to Use

It should only be administered by a trained doctor or nurse as a slow intramuscular injection. Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity and other factors.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Constipation, diarrhea Loss of appetite Nausea, vomiting Decreased RBC, WBC, and Platelets Infections Joint and muscle pain Backache, bone pain Weakness, tiredness Headache Cough, difficulty breathing Hot flushes Pain at the site of injection Serious Changes in heart rhythm Severe neutropenia(decreased WBC) Liver failure, inflammation of liver Hypersensitivity reaction Swelling in the body

Expert Tips

Inform your physician if you have vaginal bleeding, especially at starting of the therapy. This medicine is given as a shot into one of your muscles. Fulvenat 250mg injection should be used with caution in patients with severe kidney disease. This medicine needs to be given on a fixed schedule; if you miss a dose inform your doctor immediately. Do not breastfeed during treatment and for one year after your last dose. This medicine may cause infertility. Talk to your doctor before using this medicine if you plan to have children.

References

  1. Faslodex 250 mg solution for injection - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. [2020] [cited 2023 Mar 21]. Available from: https://www.medicines.org.uk/emc/product/68
  2. HIGHLIGHTS OF PRESCRIBING INFORMATION. [2017] [cited 2023 Mar 21]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021344s034lbl.pdf
  3. Goodman & Gilman’s, The Pharmacological Basics of Therapeutics, Estrogens and progestins, 12th edition, 2011, 1177.

Safety Advice

Pregnancy: unsafe Fulvenat 250mg injection is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 2 years after your last dose is necessary.

Lungs: Consult your doctor It is unknown whether Fulvenat 250mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Fulvenat 250mg injection because the medicine passes into the breast milk in small amounts and may harm your baby.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS