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Gcpeg 6mg Injection

Salt Composition: PEGFILGRASTIM

₹3094.00₹9328.13

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Gcpeg 6mg Injection contains the active ingredient Pegfilgrastim. It belongs to the class of granulocyte colony stimulating factors and is approved by the FDA to decrease the risk of febrile neutropenia (fever or infection occurring with low white blood cell count) and the duration of neutropenia (low white blood cell count) in patients receiving bone marrow suppressive chemotherapy drugs. It is also indicated to increase survival rate in patients with exposure to radiation therapy, which can cause severe and life-threatening damage to bone marrow. It acts on blood-forming cells, thereby stimulating cell multiplication and cell function activation. Pegfilgrastim is a protein synthesised through biotechnology in E. coli bacteria. It belongs to the cytokine family of proteins and is very similar to a natural protein (granulocyte-colony stimulating factor) produced by your body. White blood cells (WBC) are important because they help your body fight infection. These cells are highly sensitive to the effects of chemotherapy, which may cause a decrease in their number. If your WBC count decreases, your body may not have enough cells to combat bacteria, putting you at risk of infection. Inform your physician if you have or have ever had liver disease, fever or infection, kidney problems, heart problems, or a family history of kidney diseases before starting treatment with this Injection. Do not take this Injection if you are allergic to Pegfilgrastim, Filgrastim, or any of the other ingredients in this Injection. Report any symptoms of left upper abdominal pain, shoulder pain, and respiratory problems immediately to your doctor. The most common side effects of Gcpeg 6mg Injection are pain in the bones, arms, and legs.

Uses

Gcpeg 6mg is a prescription Injection, and it is used to treat Decrease the chance of infection caused by low levels of white blood cells in patients with certain types of cancer (non-myeloid) receiving bonemarrow suppressing anti-cancer drugs. To increase the survival rate in patients receiving radiation therapy that suppresses bone marrow activity.

How it works

Gcpeg 6mg Injection is a colony-stimulating factor that exerts its action by acting on blood-forming cells by binding to specific cell surface receptors, thereby inducing cell division, multiplication, and cell functional activation.

How to Use

The Injection will be administered in the fatty tissues just under your skin (subcutaneously) by a qualified healthcare professional in a hospital setting. The dose and frequency of administration will be decided by your doctor based on your disease condition and other factors. If your physician decides that Gcpeg 6mg Injection can be administered at home by you or your caregiver, then read the “Instructions for use” carefully from the package insert that comes with the Injection. Your doctor or other healthcare professionals will train you on self-administration. Do not administer the Injection if you have not been trained and not sure about the administration procedure.

Side Effects

Side effects are unwanted symptoms caused by Injections. Even though all drugs cause side effects, not everyone gets them. Common Pain in the bones, joints and muscles Pain at the site of Injection Itchiness and skin rash Nausea Headaches Dizziness and tiredness Serious Inflammation of Aorta Capillary leak syndrome (plasma leaks out of tiny blood vessels) Hypersensitivity reactions Changes in urine color Swelling in hands, feet, face, and abdomen Difficulty in breathing Sickle cell anemia

Expert Tips

Inform your physician if you are experiencing any symptoms of swelling in the face, feet, hands, and abdomen, difficulty in breathing, sudden drop in blood pressure, left abdominal pain, weakness, and skin rashes. Gcpeg 6mg Injection is a dose-based injection, and it should not be administered in patients weighing less than 45kg from a pre-filled syringe. Read the package insert carefully if you are self-administering the Injection. This Injection may cause lung, liver or kidney problems. Your physician may advise you to take laboratory tests regularly to monitor the effectiveness of the therapy.

References

  1. Package leaflet: Information for the user Neulasta 6 mg solution for injection pegfilgrastim. [Revised 2021 Jun] [cited 2023 Feb 23]. Available from: https://www.medicines.org.uk/emc/files/pil.10091.pdf
  2. Patient Information Neulasta ® (nu-las-tah) (pegfilgrastim) injection Single-Dose Prefilled Syringe. (2021). Available at: https://www.pi.amgen.com/-/media/Project/Amgen/Repository/pi-amgen-com/Neulasta/neulasta_ppi_pt_english.pdf [Accessed 23 Feb. 2023].
  3. HIGHLIGHTS OF PRESCRIBING INFORMATION. (2019). Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/125031s198lbl.pdf [Accessed 23 Feb. 2023].
  4. Parker, S.D. and Jacobs, T.F. (2020). Pegfilgrastim . [online] PubMed. Available at: https://www.ncbi.nlm.nih.gov/books/NBK532893/ [Accessed 23 Feb. 2023].

Safety Advice

Pregnancy: unsafe Gcpeg 6mg Injection is unsafe when administered during pregnancy because it may cause birth defects in your baby. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Lungs: Consult your doctor It is unknown whether Gcpeg 6mg Injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe It is unsafe to breastfeed during the treatment with this Gcpeg 6mg Injection because it may cause harm to the baby. Please consult your doctor before breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS