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Glenstim PEG 6mg Injection

Salt Composition: PEGYLATED GRANULOCYTE COLONY STIMULATING FACTOR

₹3157.00₹4046.72

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Glenstim PEG 6mg Injection

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Glenstim 6mg Injection contains the active ingredient pegylated granulocyte colony-stimulating factor, synthesised from the bacterium E. coli. It belongs to a class of proteins called cytokines and mimics the natural protein produced by the body. It is a leukocyte growth factor indicated to reduce infections in patients receiving anti-cancer drugs that suppress bone marrow function. By reducing infection risk, Glenstim 6mg Injection enables cancer patients to receive their full chemotherapy dose on schedule, which may improve treatment outcomes. This medication is also prescribed to increase survival in patients exposed to radiotherapy. Patients receiving Glenstim 6mg Injection may experience reduced fatigue, fewer days of fever and infection, and shorter hospital stays. This can result in improved quality of life during cancer treatment. This medication may interfere with bone marrow function testing, such as aspiration and biopsy, and cause false-positive results. Patients should inform their healthcare provider that they are receiving Glenstim 6mg Injection before undergoing any bone marrow function testing.

Uses

Chemotherapy-induced neutropenia Chemotherapy-induced fever Chemotherapy-induced infections

How it works

The therapeutic effect of the Glenstim 6mg Injection is to stimulate the production of neutrophils in the bone marrow. Neutrophils are a type of white blood cell that help to fight infections. Chemotherapy drugs can cause damage to the bone marrow, leading to a decrease in the number of neutrophils, which can increase the risk of infections. So this medication works by stimulating the bone marrow to produce more neutrophils, which can help prevent infections in cancer patients undergoing chemotherapy. This can reduce the risk of infections, hospitalizations, and other complications associated with chemotherapy-induced neutropenia.

How to Use

Glenstim 6mg Injection is administered as an injection under the skin. The injection should be given in the abdomen (at least 2 inches away from the belly button), the front of the thighs, or the upper arm. It is usually administered once per chemotherapy cycle. The medication should be administered at least 24 hours after the last dose of chemotherapy to allow for proper bone marrow recovery.

Side Effects

Like all medications, Glenstim 6mg Injection causes some side effects, although not everyone will experience them. Serious: Allergic reactions Acute respiratory distress syndrome (ARDS) Splenic rupture Kidney damage Interstitial lung disease (ILD) Common: Bone pain Headache Fatigue Muscle aches Nausea Vomiting Diarrhea Loss of appetite Injection site reactions

Expert Tips

Remember always to follow your healthcare provider's instructions when taking Glenstim 6mg Injection or any medication. Patients should be monitored for signs of an allergic reaction, such as rash, itching, or swelling, and should seek immediate medical attention if these symptoms occur. If you have any questions or concerns, do not hesitate to discuss them with your healthcare provider. Be aware of potential side effects and notify your healthcare provider if you experience any unusual symptoms. It should be used with caution in patients with severe renal impairment. Pregnant and breastfeeding women should discuss potential risks and benefits with a healthcare provider before taking this medication. Always maintain a healthy and balanced diet to support your overall health and well-being.

References

  1. Amgen Inc., [Revised on Feb 2021] [Accessed on 2 May 2023], https://www.pi.amgen.com/~/media/amgen/repositorysites/pi-amgen-com/neulasta/neulasta_pi_hcp_english.pdf
  2. Accord Healthcare Limited, Electronic Medicines Compendium (EMC), [Revised on Mar 2021] [Accessed on 2nd May 2023], https://www.medicines.org.uk/emc/files/pil.9531.pdf
  3. James L. Zehnder, Agents Used in Cytopenias; Hematopoietic Growth Factors, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 591-607
  4. Maureen S. Phillips, Pegylated granulocyte colony-stimulating factor, Clinical Journal of Oncology Nursing, 2003, 7(2), 238, https://cjon.ons.org/sites/default/files/5205800724MRU571_first.pdf

Safety Advice

Pregnancy: unsafe Glenstim 6mg Injection may harm the developing fetus, so it is unsafe to use it during pregnancy.

Lungs: unsafe Glenstim 6mg Injection may cause a side effect called interstitial lung disease (ILD), a serious lung condition that can cause symptoms such as shortness of breath, coughing, and fatigue. Patients with pre-existing lung disease may be at a higher risk of developing ILD while receiving this medicine.

Breastfeeding: Consult your doctor It is unknown whether Glenstim 6mg Injection is excreted in human milk. So breastfeeding women should consult their doctor before taking it.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS