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Golimurel 50mg Injection
Salt Composition: GOLIMUMAB
- Manufacturer: RELIANCE LIFE SCIENCES PVT LTD
- Pack Size: 1 PREFILLED SYRINGE(s) OF 0.5ML
- Dosage Form: INJECTION
- Strength: 50MG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Stored in a refrigerator at a temperature between 2°C to 8°C. Keep away from moisture, heat, and light. It should not be frozen. Keep away from children and pets.
₹18872.00₹25640.00
Inclusive of all taxes
Product Introduction
Golimurel 50mg Injection contains golimumab, a monoclonal antibody used to treat autoimmune diseases, particularly certain inflammatory conditions. It works by targeting and inhibiting a specific protein that contributes to inflammation in the body. The medication is indicated for moderate to severe rheumatoid arthritis in adults, often used in combination with other disease-modifying antirheumatic drugs (DMARDs). It is also approved for psoriatic arthritis, an autoimmune condition affecting joints and skin, and ankylosing spondylitis, a type of arthritis primarily affecting the spine and sacroiliac joints. One advantage of this medication is its relatively long dosing intervals compared with other biological medications.
Golimurel 50mg Injection should not be used in patients with known hypersensitivity or severe allergic reactions to the drug. Allergic reactions can be life-threatening and may present with symptoms such as rash, itching, swelling, severe dizziness, and difficulty breathing. This medication suppresses immune function, increasing susceptibility to infections in patients. Individuals with active infections should begin treatment only after the infection has resolved. Patients with a history of hepatitis B infection require close monitoring before starting treatment, as the virus may reactivate during therapy. Patients with a history of heart failure or other significant cardiovascular conditions require close monitoring during treatment. The safety and efficacy of Golimurel 50mg Injection in paediatric patients may differ from its use in adults. Older individuals may face higher risk of osteoporosis and fractures, and the impact of this medication on bone health should be monitored, particularly in patients already at risk. Patients with kidney impairment may require dose adjustments, as the clearance of this medication is affected by impaired kidney function.
Uses
Golimurel 50mg Injection is used in the treatment of the following: Rheumatoid arthritis Psoriatic arthritis Ankylosing spondylitis Axial spondyloarthritis Ulcerative colitis Juvenile idiopathic arthritis
How it works
Golimurel 50mg Injection is typically administered as a subcutaneous injection, which involves injecting the medication under the skin. The exact method of administration may vary depending on the specific formulation and manufacturer. Patients are often instructed to use a pre-filled syringe or an auto-injector device provided with the medication. Before self-administering, patients should follow the instructions provided by their healthcare provider and the medication's package insert.
Side Effects
Golimurel 50mg Injection causes some side effects like all medications, although not everyone will experience them. Serious Allergic reactions Elevated liver enzymes Blood disorders Immunosupression Common Injection site reactions (pain, redness, swelling) Upper respiratory tract infections (e.g., common cold) Headache Elevated liver enzymes Nausea Rash or skin reactions Upper abdominal pain Sinusitis Urinary tract infections
Expert Tips
You do not have any active infections before starting treatment with Golimurel 50mg Injection. Regular monitoring of liver function and blood counts is recommended throughout the course of treatment. Inform your doctor if you have a history of heart failure, neurological disorders, cancer, or if you require live vaccines. Stay alert for any signs of allergic reactions during treatment and report them immediately to your doctor. Pediatric and elderly patients should be closely monitored due to specific risks and required precautions. Share your complete medical history, current medications, and concerns with your healthcare provider to support safe and informed treatment decisions.
References
- Janssen Biologics BV, Electronic medicines compendium (emc), [Revised on Oct 2020] [Accessed on 25th August 2023], https://www.medicines.org.uk/emc/files/pil.5707.pdf
- Janssen Biotech, US Food and Drug Administration, [Revised on August 2011] [Accessed on 25th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/125289s0064lbl.pdf
- Eleftherios Pelechas eta l; golimumab for Rheumatoid Arthritis; Journal of Clinical Medicine; [Published on March 2019]; [Accessed on 25/08/2023]; http://www.ncbi.nlm.nih.gov/pmc/articles/pmc6463251/
Safety Advice
Pregnancy: Consult Your Doctor The safety of Golimurel 50mg Injection in pregnant women is not fully established, and its use during pregnancy requires consultation with a healthcare provider.
Lungs: Consult Your Doctor Individuals with pre-existing lung conditions, such as chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD), may already be susceptible to respiratory infections. The use of Golimurel 50mg Injection in such patients should only be done after consultation with a healthcare provider.
Breastfeeding: Consult Your Doctor The safety of using Golimurel 50mg Injection while breastfeeding is not well established, and its use during this period should be carefully considered in consultation with a healthcare provider.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.