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Grafsporin 25mg Capsule

Salt Composition: CYCLOSPORINE

₹171.00₹176.65

Inclusive of all taxes

Categories: Rheumatology

Conditions: Immune Disorder

Product Introduction

Grafsporin 25mg Capsule contains cyclosporine as its active ingredient. It is an immunosuppressant medication used primarily to prevent organ rejection in patients who have undergone organ transplantation, including kidney, liver, or heart transplants. It is used alongside other medicines to prevent the body's immune system from rejecting the new organ. Following solid organ transplantation, the body mounts an aggressive immune response as it recognises the transplanted organ's antigens as foreign. Immunosuppressive agent treatment is therefore necessary after organ transplant to prevent organ rejection.

Immunosuppressants increase the risk of skin cancer. Limit sun exposure, wear protective clothing, and use sunscreen with high sun protection factor (SPF). Inform your physician if you have recently received vaccination with live vaccines.

Grafsporin 25mg Capsule should not be used in individuals with known hypersensitivity or allergy to cyclosporine or any of its components. This medication can elevate blood pressure levels. It should be used cautiously or avoided in individuals with uncontrolled high blood pressure or a history of hypertension. Discussion of potential reproductive effects with a healthcare professional is important, particularly for individuals planning to conceive. Diabetes monitoring is important, especially for individuals at risk.

Uses

Prevention of organ rejection (Kidney, liver, and heart) Treatment of Rheumatoid arthritis and Psoriasis

How it works

By suppressing the immune system, Grafsporin 25mg Capsule helps prevent organ rejection in transplant recipients. After organ transplantation, the immune system recognizes the transplanted organ as foreign and launches an immune response to attack and reject it. Grafsporin 25mg Capsule inhibits the activation of T-cells, a type of white blood cell involved in immune responses. This suppression of T-cell activity helps to prevent the immune system from attacking and damaging the transplanted organ, thereby increasing the chances of successful organ transplantation.

How to Use

It is an orally available prescription drug. Your doctor will decide the dose and duration of Grafsporin 25mg Capsule based on the disease condition and other factors such as body weight and age. Always take this medicine as prescribed by your doctor. Take the tablet at the same time, either with or without food. Do try to break, chew, or crush the tablet. Swallow the whole tablet with a glass of water.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Kidney damage Liver damage Infection, fever or sore throat Lack of coordination Memory problems Difficulty in speaking Visual problems Seizures Confusion Personality changes Sleeplessness Agitation Common: Hypertension Electrolyte imbalance Increased level of potassium in the blood Tremor Abnormal hair growth Enlargement of gum tissues Low levels of magnesium Risk of infections Headache Gastrointestinal disturbances

Expert Tips

When using Grafsporin 25mg Capsule, it is important to take several precautions. These include monitoring infections, kidney and liver function, blood pressure, and neurological symptoms closely. Abruptly stopping this medication can increase the risk of rejection in organ transplant patients or worsening autoimmune conditions. Pregnant and breastfeeding women should consult a doctor before taking it. Regular skin examinations and vigilance for signs of malignancies are advised. Allergic reactions should be promptly addressed. Awareness of potential drug interactions and gastrointestinal side effects is crucial. Regular blood tests to monitor blood cell counts and electrolyte levels are essential. Diabetes monitoring is important, especially for individuals at risk. Pediatric and geriatric patients require special consideration. Psychological effects should be monitored, and close consultation with healthcare professionals is necessary to ensure safe and effective use of it.

References

  1. Novartis, US Food and Drug Administration, [Revised on Sep 2009] [Accessed on 25th May, 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/050715s027,050716s028lbl.pdf
  2. Novartis Pharmaceuticals UK Limited, Electronic Medicines Compendium (EMC), [Revised on March 2023] [Accessed on 25th May 2023], https://www.medicines.org.uk/emc/files/pil.1034.pdf
  3. KD Tripathi, Immunosuppressant Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019,.937-945.

Safety Advice

Pregnancy: Consult your doctor If you are taking Grafsporin 25mg Capsule and are planning to become pregnant or are already pregnant, it is important to discuss this with your healthcare professional.

Lungs: Consult your doctor It is unknown whether Grafsporin 25mg Capsule can be administered in patients with lung diseases. Inform your physician if you have any lung diseases before initiating the therapy.

Breastfeeding: unsafe Grafsporin 25mg Capsule can pass into breast milk. Mothers receiving treatment with it should not breastfeed.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS