Home › Products › Cardiology › Graftide M 500mg Tablet
Graftide M 500mg Tablet
Salt Composition: MYCOPHENOLATE MOFETIL
- Manufacturer: MYLAN PHARMACEUTICALS PVT LTD
- Pack Size: 10 TABLET(s) IN A STRIP
- Dosage Form: TABLET
- Strength: 500MG
- Prescription Required
- Storage: Store Graftide M 500mg Tablet at room temperature between (15°C to 30°C) Keep the medicine away from the reach of children and pets.
₹380.00₹691.85
Inclusive of all taxes
Product Introduction
Graftide M 500mg Tablet is an immunosuppressant containing mycophenolate mofetil as the active ingredient. It is an inosine monophosphate dehydrogenase (IMPDH) inhibitor used to prevent organ rejection in patients who have received an organ transplant, including kidney, heart, or liver transplantation. The medicine is prescribed as part of combination therapy with other immunosuppressive drugs.
This medicine is contraindicated in pregnancy due to the risk of birth defects and miscarriage. It should not be used in pregnant women unless no suitable alternatives exist and the potential benefits justify the risks. Women of childbearing age should use effective contraception during treatment to prevent pregnancy.
Live vaccines must not be administered while taking Graftide M 500mg Tablet due to reduced vaccine effectiveness and increased risk of infection. Patients should not donate blood during treatment and for at least six weeks after discontinuing the medication to ensure adequate clearance from the body.
Do not take this medicine if you are allergic to mycophenolate mofetil or any other components. Inform your doctor of existing liver or heart disease before starting treatment. As this drug suppresses immune defenses, it increases the risk of skin cancer. Patients should take precautions to limit exposure to sunlight and ultraviolet (UV) light.
Seek immediate medical attention if you develop bruising under the skin, fever, unexplained tiredness, dizziness, yellowing of the skin or eyes, vision impairment, reduced urine output, or seizures after taking this medicine.
Graftide M 500mg Tablet is an immunosuppressive medication that may affect the infant's developing immune system and should be avoided during breastfeeding. In some cases, alternative medications with a more favourable safety profile during breastfeeding may be considered.
Uses
Prevent organ transplant rejections
How it works
Graftide M 500mg Tablet works by inhibiting the enzyme inosine monophosphate dehydrogenase (IMPDH) and reducing the production of guanosine nucleotides. MMF specifically affects the proliferation of activated T and B lymphocytes. These lymphocytes are key players in the immune response that can lead to the rejection of a transplanted organ
How to Use
It is an orally available prescription drug. Your physician will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. Always take Graftide M 500mg Tablet as prescribed by your doctor. Do not open, crush, break, or chew the medicine.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Infections, fever, or sore throat Unusual bleeding or bruising Low blood cell count Severe allergic reactions Common Higher risk of developing lymphoma and other cancers Nausea, abdominal pain Diarrhea Constipation Loss of appetite Shortness of breath Weight loss Increased heartbeat Headache Blood pressure problem Anaemia
Expert Tips
It is necessary to take the prescribed dose exactly as instructed by your doctor. Inform your doctor about all the medications (prescription, over-the-counter, and herbal) you are taking, as they can interact with this drug. If you plan to conceive or suspect you might be pregnant while taking Graftide M 500mg Tablet, it is important to consult your doctor immediately. They may suggest switching to alternative medications that are safer during pregnancy or adjusting your treatment plan.
References
- Roche Products Limited, European Medicine Consortium (EMC), [Revised on April 2022],[Accessed on 25/05/2023], https://www.medicines.org.uk/emc/files/pil.1103.pdf
- Genentech USA, Inc., [ Revised on Oct 2021] [ Accessed on 25/05/2023], https://www.gene.com/download/pdf/cellcept_prescribing.pdf
- S.E. Marshall, Immunological Factors in Disease, Davidson's Principles and Practice of Medicine, 22nd Edition, 2014, 71-96.
- KD Tripathi, Immunosuppressant Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019,.937-945.
- Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Inflammation, Immunomodulation, and Hematopoiesis, 12th Edition, 2011, 1014.
Safety Advice
Pregnancy: unsafe Graftide M 500mg Tablet is known to have harmful effects on the developing fetus and is generally not prescribed for use during pregnancy unless the benefits outweigh the risks.
Lungs: Consult your doctor Graftide M 500mg Tablet should be cautiously administered in patients with lung diseases. Dose adjustments are necessary. Inform your physician if you have lung problems before initiating the therapy.
Breastfeeding: unsafe Graftide M 500mg Tablet is not recommended for breastfeeding mothers because small amounts of the drug can pass into the mother's milk and affect the nursing baby.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.