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Halsbev 100mg Injection
Salt Composition: BEVACIZUMAB
- Manufacturer: HALSTED PHARMA PVT. LTD.
- Pack Size: 1 VIAL(s)
- Dosage Form: INJECTION
- Strength: 100MG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Store at 2-8ËC Protect from light. Keep children away from the sight and reach of this medication.
₹6883.00₹20000.00
Inclusive of all taxes
Product Introduction
Halsbev 100mg Injection is a monoclonal antibody containing bevacizumab. It is indicated for treatment of advanced colorectal cancer (colon or rectum) in adults, administered alongside chemotherapy. Additional indications include metastatic breast cancer, advanced non-small cell lung cancer, renal cancer, advanced epithelial ovarian cancer, fallopian tube cancer, primary peritoneal cancer, and persistent or recurrent cervical cancer.
Inform your doctor of any allergy to Halsbev 100mg Injection or its ingredients. Medical consultation is recommended if you have abdominal inflammation, cervical cancer, bleeding risk, impaired wound healing, or unhealed surgical wounds. Advise your doctor of skin infection, hypertension, aneurysm, arterial or venous thrombosis risk, bleeding disorders, or cardiac conditions. A dental examination before commencing treatment may be advised. Notify your doctor or dentist immediately if you experience oral or jaw pain, intraoral swelling, jaw numbness, or tooth loosening during treatment. Safety and efficacy have not been established in patients below 18 years of age. Discuss with your doctor if you are planning pregnancy, suspect pregnancy, or are breastfeeding. Patients aged over 65 years may face increased risk of stroke or myocardial infarction, reduced white blood cell and platelet counts, diarrhoea, nausea, headache, fatigue, and hypertension whilst receiving treatment.
Uses
Advanced stage of large intestine cancer Metastatic breast cancer Advanced non-small cell lung cancer Advanced kidney cancer Advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer Persistent, recurrent cervical cancer
How it works
Halsbev 100mg Injection is a recombinant humanized monoclonal antibody that works as a targeted therapy in the treatment of various advanced cancers. It produces its action by selectively binding to the vascular endothelial growth factor A (VEGF-A) protein, which is present in the lining of blood and lymph vessels in the body. It interrupts the interaction of VEGF-A with its receptors. This further inhibits the formation of blood vessels that supply oxygen and nutrients to the tumor. As a result, it slows down the rate of progression of cancer.
How to Use
This medicine is given only in a hospital by a healthcare provider. Your doctor will provide you with Halsbev 100mg Injection intravenously (into a vein). Your physician will decide the dosage and frequency of this injection based on the severity of your disease and other factors.
Side Effects
Side effects are unwanted symptoms caused by medicines. Although all drugs cause side effects, not everyone experiences them. Serious: High blood pressure Feeling of numbness or tingling in hands or feet Decreased blood count Lack of energy and tiredness Diarrhea Nausea Vomiting Abdominal pain. Gut problem (perforation) Bleeding or blood clotting disorder Heart failure Wound healing problem (surgery) Stomach or intestinal disorder Muscle problem Dry mouth, thirst, or reduced urine Inflammation of the linings in the mouth, gut, lung and air passage, reproductive and urinary tract) Sore mouth Pain (back, pelvis or anal regions) Pus Infection Sleepiness Nose bleeding Allergic reactions (the signs may include breathing difficulty, facial redness, rash, low blood pressure or high blood pressure, chest pain, or nausea/vomiting) Common: Constipation Loss of appetite Fever Problems with the eyes (including increased production of tears), Changes in speech Change in the sense of taste Runny nose Dryness or inflammation of the skin Loss of body weight Nose bleeds Voice changes and hoarseness
Expert Tips
Drinking at least two liters of water and eating a healthy diet that contains fiber may help you recover from constipation. Sufficient amounts of water and electrolytes help compensate for the water loss caused by diarrhea and vomiting. Your doctor may recommend you to check your blood pressure level before taking the medicine. Avoid smoking, drinking alcohol, and eating foods that irritate your mouth.
References
- Roche Products Limited, Electronic Medicines Compendium (EMC), [Revised on Nov 2022] [Accessed on 02/04/2023], https://www.medicines.org.uk/emc/files/pil.3885.pdf
- G.G. Dark, A.R. Abdul Razak, Oncology, Davidson's Principles & Practice of Medicine, 22nd Edition, 2014, 259-282.
- KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.
- Edward Chu, Cancer Chemotherapy, Langeâs Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
- Genentech, Inc., U.S FDA, [Revised on Sep 2022][ Accessed on 02/04/2024], https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/125085s340lbl.pdf
- Roche Group,Halsbev 100mg Injection Injection, Indication,[Revised on 2020] [Accessed on 21/11/2022] https://www.avastin.com/patient/mcrc.html
Safety Advice
Pregnancy: Consult your doctor Limited information is available on the use of Halsbev 100mg Injection during pregnancy. Notify your healthcare professional if you are pregnant or planning to have a baby. If you think you may be pregnant.
Lungs: Consult your doctor It is unknown whether Halsbev 100mg Injection is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Breastfeeding: Consult your doctor Limited information is available on using Halsbev 100mg Injection during breastfeeding. So, before starting the treatment, inform your doctor if you are breastfeeding. Contact your doctor for more details.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.