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Hemlibra 60mg Injection

Salt Composition: EMICIZUMAB

₹86747.00₹102258.00

Inclusive of all taxes

Hemlibra 60mg Injection

Categories: Hematology

Conditions: Blood Disorder

Product Introduction

Hemlibra 60mg Injection contains emicizumab, a monoclonal antibody. It is indicated for patients with haemophilia A who have developed factor VIII inhibitors, and for patients with severe haemophilia A who have not developed factor VIII inhibitors (factor VIII blood level less than 1%). Haemophilia A is an inherited disorder resulting from deficiency of factor VIII, a substance essential for blood clotting and haemostasis. Monoclonal antibodies are proteins that recognise and bind to specific targets in the body. This medicine reduces bleeding episodes in patients with this condition.

Do not use Hemlibra 60mg Injection if you are allergic to emicizumab or any other ingredients in the formulation. Before starting treatment, inform your doctor of all other medications you are taking. Report to your physician immediately if bleeding occurs following administration of this medicine. This injection may be used across all age groups. Do not inject into areas where the skin is red, bruised, tender, hard, or where moles or scars are present.

Uses

Hemophilia A

How it works

Hemlibra 60mg Injection binds to activated factor IX and factor X to restore function to the coagulation cascade and promote hemostasis. It restores the function of missing activated factor VIII, which is needed for effective blood clotting. Its structure differs from factor VIII; therefore, the medicine is unaffected by factor VIII inhibitors.

How to Use

Hemlibra 60mg Injection will be given by injection under the skin (subcutaneous). Your doctor or nurse or other healthcare professional will show you how to inject the medicine. Do not try to administer the medicine if you are well-trained. Your physician will decide the dose of the injection based on your disease condition and severity. The recommended places to give an injection are the front of the waist (lower abdomen), upper outer arms, or the front of the thighs. Use only recommended places for injection. ● For each injection, use a different area of the body than the one you used last time.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Injection site reactions Joint pain Headache Serious Heart problems Muscle cramps and pain Blood clot Bleeding Destruction of red blood cells

Expert Tips

This medicine is given as a shot under your skin. It is usually injected into the upper outer arms, thighs, or stomach. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. Do not inject into skin areas that are tender, red, bruised, hard, or not intact, or into areas with moles or scars. Use a new needle and syringe each time you inject your medicine. Women should use an effective form of birth control to keep from getting pregnant. Tell your doctor right away if you think you have become pregnant. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

References

  1. Hemlibra 150 mg/mL Solution for Injection - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published September 2022. Accessed May 10, 2023. http://www.medicines.org.uk/emc/product/9043/smpc
  2. Emicizumab Injection, Highlights of Prescribing Information, Revised 2017. Accessed May 10, 2023. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/761083s000lbl.pdf
  3. H.G. Watson, J.I.O. Craig, L.M. Manson, Blood disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 989-1056.
  4. Le Quellec, Clinical Evidence and Safety Profile of Emicizumab for the Management of Children with Hemophilia A, Drug Design, Development and Therapy, 2020:14, https://www.dovepress.com/getfile.php?fileID=55818

Safety Advice

Pregnancy: unsafe Do not take Hemlibra 60mg Injection if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for 6 months after the last dose.

Lungs: Consult your doctor It is unknown whether Hemlibra 60mg Injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Hemlibra 60mg Injection because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS