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Heptral 400mg Tablet

Salt Composition: ADEMETIONINE

₹1167.00₹1457.51

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Heptral 400mg Tablet

Categories: Hepatology

Conditions: Liver Disease

Product Introduction

Heptral 400mg tablet contains ademetionine as its active component. It is used to treat intrahepatic cholestasis, a condition characterised by reduced bile flow from the liver. The medication is also indicated for other liver diseases, including cirrhosis and alcoholic hepatitis. Heptral is effective in treating major depressive disorder. It works by promoting bile production, a fluid essential for fat digestion and toxin removal from the body. The tablet is also used to manage osteoarthritis pain and inflammation by reducing production of inflammatory chemicals and promoting cartilage repair.

Do not take Heptral 400mg tablet if you are allergic to ademetionine or any other ingredient in the medication. This medication may trigger manic episodes in people with bipolar disorder and is not recommended for this population. Safety has not been established in pregnant or breastfeeding women, so use should be avoided during these periods. It may be harmful in people with severe kidney function impairment. Heptral 400mg should not be used in people with Parkinson's disease, as it may worsen symptoms. Avoid use in homocystinuria, as it may worsen symptoms. The medication is generally safe for older adults; however, consultation with a healthcare provider is important before use in this age group. Ademetionine has not been extensively studied in children and should be avoided in this population unless specifically recommended by a doctor.

Uses

Heptral 400 tablet uses include: Hepatoprotective Antidepressant Chondroprotective Antioxidant Nootropic

How it works

Ademetionine works by donating methyl groups to other molecules, which is essential for many cellular functions, including DNA repair, gene expression, and protein synthesis. It is also a precursor to glutathione, a powerful antioxidant that protects cells from damage. Additionally, it is involved in the production of bile, which helps to digest fats and remove toxins from the body.

How to Use

Ademetionine can be administered orally, intravenously, intramuscularly, or rectally. The route selection depends on the specific condition being treated and the intended therapeutic effect. Heptral 400 dosage should be adjusted based on the patient's medical condition and response to treatment.

Side Effects

Heptral 400 mg side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. The heptral 400 side effects are: Serious Allergic reactions Mania or hypomania Serotonin syndrome Worsening liver disease Common Abdominal discomfort Nausea and vomiting Headache Dizziness Insomnia Anxiety

References

  1. Abbott Laboratories, [Accessed on 25th Oct 2023], https://www.medicine.abbott/content/dam/bss/divisionalsites/epd/productpdf/Transmetil%20500mg.pdf
  2. Mazen Noureddin et al., Early treatment efficacy of S-adenosylmethionine in patients with intrahepatic cholestasis: A systematic review;[Published on Feb 2020][Accessed on 25th Oct 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061266/
  3. S-adenosylmethionine; [Accessed on 25th Oct 2023]; http://accurateclinic.com/wp-content/uploads/2016/02/S-adenosylmethionine-University-of-Maryland-Medical-Center. pdf#2

Safety Advice

Pregnancy: Consult your doctor Ademetionine has not been studied extensively in pregnant women, so it is best to avoid it during these times.It is important to consult with a healthcare provider to assess the individual situation.

Lungs: Consult your doctor Consult your healthcare provider if you have a history of lung conditions before using the Ademetionine.

Breastfeeding: Consult your doctor It is important to consult with a healthcare provider before taking Ademetionine as it has not been studied extensively in breastfeeding women.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS