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Hivus LR Tablet

Salt Composition: LOPINAVIR,RITONAVIR

₹1857.00₹2694.38

Inclusive of all taxes

Hivus LR Tablet

Categories: Infectious Disease

Conditions: Antiviral

Product Introduction

Hivus LR Tablet is an antiretroviral medication in the protease inhibitor class, containing lopinavir and ritonavir as active ingredients. It is indicated for treatment of HIV-1 infection. HIV-1 is a human immunodeficiency virus that progressively attacks and weakens the immune system, making patients with this infection increasingly susceptible to opportunistic infections.

Patients with hepatitis B, hepatitis C, or other liver disorders may face an elevated risk of developing new or worsening liver disease during treatment with Hivus LR Tablet. Inform your healthcare provider immediately if you develop signs or symptoms of liver problems, including loss of appetite, dark-coloured urine, yellow discolouration of the skin and whites of the eyes (jaundice), or pale-coloured stools.

Patients with elevated triglyceride levels have an increased risk of developing pancreatitis, an inflammatory condition of the pancreas. Those with a history of pancreatitis face a greater chance of recurrence during treatment with this medication.

During early stages of HIV-1 treatment, some patients may experience an inflammatory response to opportunistic infections, a condition known as immune reconstitution syndrome. This may occur after initiating this drug or other antiretroviral therapies. Monitor for signs of worsening infections or inflammatory symptoms, and inform your healthcare provider if such symptoms develop or persist longer than expected.

Avoid this medication if you are allergic to lopinavir, ritonavir, or any other ingredients in the formulation. Inform your doctor of all medications you are currently taking, including herbal preparations and supplements, prior to commencing treatment with this drug.

Uses

Treatment of HIV-1 infection

How it works

Hivus LR Tablet work together to inhibit the protease enzyme, which is necessary for the replication of HIV. By blocking this enzyme, this drug prevents the virus from multiplying and spreading in the body. It mainly helps reduce the viral load and slow the progression of HIV infection.

How to Use

It is an orally available prescription drug. Your doctor will decide the dose and duration of the drug based on the disease condition and other factors. Always take Hivus LR Tablet as prescribed by your doctor. Take the tablet with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Osteonecrosis (stiffness and pain in joints, difficulty moving) Lactic acidosis (breathing difficulties along with weakness in limbs, stomach pain, and drowsiness) Symptoms of muscle weakness or infection Changes in body fat Inflammation of the pancreas (nausea, vomiting, along with abdominal pain) Liver problems (yellow skin and whites of eyes, dark-colored urine, pale-colored stools, loss of appetite) High blood sugar (Increased thirst or urination) Severe allergic reactions Common Diarrhea Increased lipid levels in the blood

Expert Tips

To prevent the spread of HIV infection, avoid sharing needles or syringes, which can transmit HIV-1 infections easily. It's necessary for individuals who use injectable drugs to use sterile needles and syringes and never share them with others. Personal items like toothbrushes, razor blades, or anything with body fluids or blood on them should also be avoided. They should not be shared because HIV-1 can be present in blood and certain body fluids, and sharing these items could mainly transmit the virus. Since this drug is unsafe for breastfeeding because HIV infection can be passed to the baby in the breast milk, alternative feeding methods can be followed to nourish the infant's growth. If you forget to take Hivus LR Tablet for the entire day, take your usual dose the next day. However, do not double-dose yourself.

References

  1. AbbVie Deutschland GmbH & Co. KG, Electronic medicines compendium (EMC), [ Revised on March 2021] [ Accessed on 17th May 2023], https://www.medicines.org.uk/emc/files/pil.221.pdf
  2. AbbVie Inc, US Food and Drug Administration, [ Revised on December 2018] [ Accessed on 17th May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/pepfar/090371PI.pdf
  3. KD Tripathi, Essentials of Medical Pharmacology, Antiviral drugs, 7th edition, 2013, 809 - 811.
  4. Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Antiretroviral agents and treatment of HIV infection, 12th edition, 2011, 1645-1654.

Safety Advice

Pregnancy: Consult your doctor Your doctor shall prescribe Hivus LR Tablet only if it is essential and the benefits outweigh the risks.

Lungs: Consult your doctor It is unknown whether Hivus LR Tablet can be prescribed for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Taking Hivus LR Tablet during breastfeeding is unsafe because it tends to get excreted in human milk

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS