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Hydrozest 500mg Capsule 10's

Salt Composition: HYDROXYUREA

₹101.00₹127.00

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Hydrozest Capsule is an anticancer medication containing the active ingredient Hydroxyurea. It is used to treat chronic myeloid leukaemia (cancer of white blood cells) and polycythemia vera (cancer of red blood cells). This medication works by slowing down the growth and division of cancer cells. It is indicated for the treatment of cervical, ovarian, and melanoma (skin cancer) and head and neck cancer. In patients with sickle cell anaemia (an inherited blood disease characterised by insufficient healthy red blood cells), this medication reduces the frequency and severity of painful episodes and helps prevent organ damage.

Cancer is a disorder in which cells multiply in an uncontrolled and abnormal manner. This medication may be used to treat other conditions not mentioned here. Before taking Hydrozest 500mg Capsules, inform your physician if you have any blood disorders, severe anaemia, kidney disorders, liver disorders, gout, leg ulcers, folic acid deficiency, or intolerance to some sugars.

Uses

Hydrozest Capsule is approved for the following conditions: Ovarian cancer Polycythemia vera Chronic myeloid leukemia Cervical cancer Head and neck cancer Sickle cell anemia

How it works

In cancer, Hydrozest Capsule works by slowing down the growth and division of cancer cells, which can help to shrink tumors and prevent the spread of cancer to other parts of the body. This can lead to a reduction in the size and number of tumors, which may improve symptoms and increase survival rates. In sickle cell anemia, this medication works by increasing the production of fetal hemoglobin, which can help to prevent the abnormal shaping of red blood cells. This can reduce the frequency and severity of painful episodes, prevent damage to organs, and improve the overall quality of life. It also reduces the need for blood transfusions and hospitalizations. It prevents complications such as stroke, acute chest syndrome, and pulmonary hypertension.

How to Use

Hydrozest Capsules should be taken exactly as prescribed by a healthcare provider. It is typically taken orally in the form of a capsule or tablet, usually once a day or as directed by the healthcare provider. The medication should be taken with a full glass of water and can be taken with or without food, depending on the individual's preference and tolerability. If a dose is missed, it should be taken as soon as possible unless it is close to the time for the next scheduled dose. In that case, the missed dose should be skipped, and the regular dosing schedule should be resumed. It is important not to take a double dose to make up for a missed dose.

Side Effects

Like all medications, Hydrozest Capsule can cause side effects, although not everyone who takes it will experience them. Serious: Bone marrow suppression (decreased blood cell count) Skin reactions (rash, itching, and skin ulcers) Stevens-Johnson syndrome (life-threatening skin reaction) Tumor lysis syndrome (occur when large numbers of cancer cells are killed rapidly) Liver damage (jaundice, dark urine, pale stools, nausea, vomiting, and abdominal pain) Lung toxicity (shortness of breath, cough, fever, and chest pain) Common: Nausea Vomiting Diarrhea Loss of appetite Mouth sores Headache Dizziness Fatigue Skin darkening Hair loss or thinning Nail changes Constipation

Expert Tips

Hydrozest Capsule is a powerful medication that can have potentially serious side effects. Therefore, following your healthcare provider's instructions for taking the medication and reporting any side effects or changes in your health is important. Women taking contraceptives should inform a doctor before the treatment. If you are a woman who could become pregnant, use effective birth control during the treatment and for at least three months after the last dose. Tell your doctor if you have any liver, lung, or kidney disease before taking medication. You should use sun protection while taking this medication It is recommended that patients undergoing cancer treatment eat a diet rich in fruits, vegetables, whole grains, and lean proteins and limit their intake of processed and high-fat foods. Drinking plenty of water and staying hydrated is also important.

References

  1. Bristol-Myers Squibb Pharmaceuticals Unlimited Company, Electronic medicines compendium (EMC), [Revised on August 2021] [ Accessed on 17 April 2023], https://www.medicines.org.uk/emc/files/pil.271.pdf
  2. Bristol-Myers Squibb Company, US Food and Drug Administration, [Revised on March 2016] [ Accessed on 17th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/016295Orig1s047,s048Lbl.pdf
  3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1721.
  4. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 868.
  5. Rohit Kumar Agarwal et al; Hydroxyurea in Sickle Cell Disease: Drug Review; Indian Journal of Hematology & Blood Transfusion; Published on June 2014; Accessed on 17 April 2023; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022916/#__ffn_sectitle

Safety Advice

Pregnancy: unsafe Hydrozest Capsules are not safe for use during pregnancy because they can harm the developing baby. You need to tell your physician if you are pregnant or planning to get pregnant before taking this medicine.

Lungs: unsafe Hydrozest Capsule can cause lung toxicity, although this is a rare side effect. If you have pre-existing lung problems or a history of radiation therapy to the lungs, you should tell your healthcare provider before taking this medication.

Breastfeeding: unsafe It is not safe to take Hydrozest Capsules while breastfeeding. It has been shown to pass into breast milk, and its affects the nursing infant. Because of this, women who are taking this medication should avoid breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS