Ibrumed 140mg Capsule

Ibrumed 140mg Capsule contains the active ingredient ibrutinib. It is indicated for treatment of blood cancers including mantle cell lymphoma (MCL), chronic lymphocytic leukaemia (CLL), small lymphocytic lymphoma (SLL), Waldenström macroglobulinaemia, and marginal zone lymphoma (MZL). These are cancers of white blood cells called lymphocytes, which form part of the immune system. They differ from each other based on the location where cancer occurs, the type of lymphocytes affected, and certain other factors. Ibrumed 140mg Capsule is also used to treat chronic graft versus host disease (cGVHD) following failure of systemic therapy. During allogeneic stem cell transplantation, patients receive stem cells from a donor. GVHD occurs when donor cells recognise the patient's cells as foreign and attack them. Before taking this medicine, you should discuss with your physician if you have bleeding disorders, infection, liver problems, heart problems, or intolerance to certain sugars. This medication is not recommended for adolescents and children. It is important to inform your physician if you have recently undergone or are scheduled to undergo any surgical procedure. Your physician may discontinue Ibrumed 140mg Capsule for any planned surgical or medical procedure. Use effective birth control during treatment and for at least one month after the final dose. Avoid grapefruit or oranges in any form during this treatment, as they may increase the amount of drug in the blood. Drink adequate fluid to prevent dehydration. Inform your physician if you experience diarrhoea that does not resolve.

Mantle cell lymphoma Chronic lymphocytic leukemia (Blood cancer) Small lymphocytic lymphoma Waldenstrom’s macroglobulinemia Chronic graft vs. host disease after failure of systemic therapy

The mechanism of action of Ibrumed 140 mg involves blocking a specific protein called Bruton's tyrosine kinase (BTK) which plays a key role in the survival and growth of cancer cells. By inhibiting BTK, Ibrumed 140 mg prevents the cancer cells from receiving the signals they need to grow and divide, leading to their eventual death.

Consume this medicine at the same time each day. While taking Ibrumed 140 mg capsule, do not consume grapefruit or orange in any form during the treatment. Drink plenty of fluid to prevent dehydration.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Bleeding problems Infections Decrease in blood cell counts. Heart problems High BP Secondary cancer Tumor lysis syndrome Severe allergic reactions Common: Nausea, vomiting, diarrhea Tiredness Muscle and bone pain Rash and bruising Mouth sores Pneumonia Fever, chills Breathlessness Constipation Dizziness Body pain Swollen ankles and feet Increased creatinine levels in blood Heavier periods and blood in urine Blurred vision Weakness and numbness

Contact your doctor immediately if you experience bleeding, infection, shortness of breath, or chest discomfort. Report to your doctor if you have had a history of heart failure or hepatitis infection. It is not recommended to take this medicine before or after surgery as it causes a delay in wound healing. Discuss effective contraceptive options with your healthcare provider and use them during treatment and for a month after the last dose of Ibrumed140mg.