Ibrunat 140mg Capsule

Ibrunat 140mg Capsule contains the active ingredient Ibrutinib. It is indicated for the treatment of blood cancers including mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), Waldenstrom's macroglobulinemia, and marginal zone lymphoma (MZL). These are cancers of white blood cells called lymphocytes, which form part of the immune system. They vary in location of cancer development, the type of lymphocytes affected, and other distinguishing characteristics.

Ibrunat 140mg Capsule is also used to treat chronic graft versus host disease (cGvHD) following failure of systemic therapy. During allogeneic stem cell transplantation, patients receive stem cells from a donor. GvHD occurs when donor cells recognize the patient's cells as foreign and attack them.

Before taking Ibrutinib Capsule, discuss with your physician if you have bleeding disorders, infection, liver problems, cardiac problems, or intolerance to certain sugars. This medication is not recommended for children and adolescents. Inform your physician if you have recently undergone or are scheduled for any surgical procedure. Your physician may discontinue Ibrunat 140mg Capsule in advance of any planned surgical or medical procedure.

Use effective contraception during treatment and for at least one month after the final dose of Ibrunat. Avoid grapefruit and oranges in all forms during treatment, as they may increase drug concentration in the blood. Maintain adequate fluid intake to prevent dehydration. Report to your physician if you experience persistent diarrhea.

Ibrunat uses in the treatment of Mantle cell lymphoma Chronic lymphocytic leukemia (Blood cancer) Small lymphocytic lymphoma Waldenstrom’s macroglobulinemia Chronic graft vs. host disease after failure of systemic therapy

The mechanism of action of Ibrunat capsule involves blocking a specific protein called Bruton's tyrosine kinase (BTK) which plays a key role in the survival and growth of cancer cells. By inhibiting BTK, Ibrunat 140mg prevents the cancer cells from receiving the signals they need to grow and divide, leading to their eventual death.

Consume Ibrunat 140mg at the same time each day. While taking Ibrunat 140mg, do not consume grapefruit or orange in any form during the treatment. Drink plenty of fluid to prevent dehydration.

Ibrunat side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Bleeding problems Infections Decrease in blood cell counts Heart problems High BP Secondary cancer Tumor lysis syndrome Severe allergic reactions Common Nausea, vomiting, diarrhea Tiredness Muscle and bone pain Rash and bruising Mouth sores Pneumonia Fever, chills Breathlessness Constipation Dizziness Body pain Swollen ankles and feet Increased creatinine levels in blood Heavier periods and blood in urine Blurred vision Weakness and numbness