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Iflurane 30ml Liquid FOR Inhalation

Salt Composition: ISOFLURANE

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Iflurane 30ml Liquid FOR Inhalation

Categories: Others

Conditions: Anaesthetics

Product Introduction

Iflurane 30ml Liquid For Inhalation contains Isoflurane as its active component. It is a volatile inhalation anesthetic used in anaesthesia and surgery. It belongs to a class of halogenated ethers, which induce and maintain general anaesthesia. It may be used for emergency surgeries, including trauma cases and surgeries for life-threatening conditions, where rapid induction of anaesthesia is required. It can be used for certain diagnostic and therapeutic procedures requiring general anaesthesia. Although less commonly used during childbirth due to concerns about uterine relaxation, it may be used in some situations during caesarean sections when other anaesthetics are unsuitable. Before administration, a thorough assessment of the patient's health and an individualised anaesthesia plan is typically established to ensure safety and effectiveness during the procedure. Patients with known allergy or hypersensitivity to Isoflurane or other halogenated ethers should not receive it. As the liver metabolises it to a small extent, patients with severe liver dysfunction should not take this medication. Patients with a personal or family history of malignant hyperthermia should also avoid it. Patients with severe respiratory disorders, such as advanced chronic obstructive pulmonary disease (COPD), may require careful consideration of its risks and benefits. Patients with unstable cardiovascular conditions, such as uncontrolled hypertension or severe arrhythmias, may require careful monitoring. It can be used in older adults when appropriate precautions are taken. Isoflurane is suitable for paediatric patients undergoing surgery, as it can be titrated to provide the appropriate level of anaesthesia for children.

Uses

Isoflurane is used in the following: General anesthesia Surgical procedures Emergency surgery Diagnostic and therapeutic procedures Pediatric surgery Veterinary medicine

How it works

Iflurane 30ml Liquid For Inhalation induces and maintains general anesthesia by altering the activity of neurotransmitters in the central nervous system. It enhances the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), which reduces the transmission of signals between nerve cells. This leads to a reversible loss of consciousness, amnesia, analgesia (pain relief), and muscle relaxation, ensuring that patients remain immobile and pain-free during surgical procedures.

How to Use

Iflurane 30ml Liquid For Inhalation is typically administered through inhalation, specifically by using a specialized anesthesia delivery system. It is inhaled as a vapor to induce and maintain general anesthesia during medical and surgical procedures.

Side Effects

Iflurane 30ml Liquid For Inhalation causes side effects like all medications, although not everyone will experience them. Serious Respiratory depression Cardiovascular effects Malignant hyperthermia Allergic reactions Liver and kidney function changes Neurological effects Common Nausea and vomiting Headache Sore throat and cough Shivering Confusion or memory changes

Expert Tips

Before taking Iflurane 30ml Liquid For Inhalation, a thorough patient assessment is conducted, including medical history, allergies, and preexisting conditions. Continuous monitoring of vital signs, ventilation, and anesthetic depth is maintained throughout the procedure to promptly detect and address any changes in the patient's condition. Attention is given to proper patient positioning to prevent pressure ulcers and nerve damage. Infection control measures are rigorously observed to minimize the risk of surgical site infections. Adequate fluid management and intravenous support are administered to maintain hydration and circulation.

References

  1. Piramal Critical Care Ltd, Electronic Medicines Compendium (EMC), [Revised on 29th Oct 2019] [Accessed on 5th September 2023], https://www.medicines.org.uk/emc/product/1792/smpc#gref
  2. Baxter Healthcare Corporation, US Food and Drug Administration, [Revised on Nov 2022 ] [Accessed on 5th September 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/017624s042lbl.pdf
  3. Christina L. Torturo et al., Isoflurane Inhibits Dopaminergic Synaptic Vesicle Exocytosis Coupled to CaV2.1 and CaV2.2 in Rat Midbrain Neurons, eNeuro, 2019, 6 (1), https://www.eneuro.org/content/eneuro/6/1/ENEURO.0278-18.2018.full.pdf
  4. KD Tripathi, General anesthetics, Essentials of Medical Pharmacology, 8th Edition, 2019, 399-414.

Safety Advice

Pregnancy: Consult your doctor Iflurane 30ml Liquid For Inhalation is unsafe during pregnancy, especially during the first trimester, due to concerns about potential effects on the developing fetus.

Lungs: Consult your doctor Iflurane 30ml Liquid For Inhalation is generally not associated with adverse effects on lung health. However, consult your healthcare provider if you have specific concerns or lung conditions.

Breastfeeding: Consult your doctor If you need to take Iflurane 30ml Liquid For Inhalation while breastfeeding, it's crucial to discuss the risks and benefits with your healthcare provider.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS