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Ifosym 1gm Injection

Salt Composition: IFOSFAMIDE

₹402.00₹502.61

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Ifosym 1gm Injection

Categories: Oncology, Other, Cancer & Oncology

Conditions: Anti Cancer, Hemorrhagic Cystitis (Bladder Inflammation), Soft Tissue Cancer, Germ Cell Cancer, Pancreatic Cancer, Cervical Cancer

Product Introduction

Ifosym 1gm Injection is an anticancer medication classified as an alkylating agent, containing the active ingredient Ifosfamide. It is indicated for treatment of bladder inflammation and cancers of soft tissues, germ cells, pancreas and cervix. This drug should not be used if patients have an allergic reaction to Ifosfamide or any of its components. The medication may cause severe bone marrow suppression, resulting in low white blood cell count or low platelet count due to chemotherapy or radiation therapy. Patients should wait three months before starting treatment with this drug if they have received a live virus vaccine for measles, mumps, rubella or chickenpox. Use with caution is advised in patients with severe kidney or liver disease. Inform your doctor if you are taking any other medications or plan to use over-the-counter medicines or herbal products, as your doctor will evaluate the risk of interaction with this medication. Do not use Ifosym 1gm Injection if you are pregnant or planning to have a baby, as it causes harm to an unborn fetus. Your healthcare practitioner will conduct a pregnancy test before starting treatment with Ifosym 1gm Injection. Discuss with your doctor effective birth control methods and use them for at least two weeks following the last dose. Breastfeeding should be avoided during treatment with this drug as it may pass into breast milk in small amounts.

Uses

1. Hemorrhagic cystitis (bladder inflammation) 2. Soft tissue cancer 3. Germ cell cancer 4. Pancreatic cancer 5. Cervical cancer

How it works

It works by damaging the DNA in cancer cells, which leads to cell death and slows the growth and spread of cancer. Mostly, this involves the formation of reactive metabolites in the liver, which are then transported to cancer cells in the body. These metabolites react with the DNA in the cancer cells, causing cross-links and breaks in the DNA strands. This interferes with the replication and transcription of DNA, leading to cell death.

How to Use

It will be given to you by a doctor or nurse in a hospital or clinic setting trained in cancer chemotherapy. It is given as an intravenous infusion drip (into your vein). Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity, body weight, and other factors.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Immune system suppression Low levels of RBC, WBC and platelets in the blood Bone marrow suppression Nerve toxicity Urinary problems Lung problems Kidney problem Common Hair loss Fever Phlebitis Liver toxicity Infections

Expert Tips

This injection may cause severe birth defects if taken during pregnancy. Female patients with reproductive potential should use effective contraception during the treatment. Male patients with female partners with reproductive potential should use effective birth control methods during the treatment and for at least 5 months after their last dose. Do not breastfeed during treatment with this injection. Your doctor may advise you to take certain tests to check for the effectiveness of the therapy. Ifosym 1gm Injection may cause dizziness, drowsiness, or blurred vision, so it is important to avoid driving. It's important to avoid consuming grapefruit or grapefruit juice while taking this injection because this can lead to increased levels of the drug in your body and a higher risk of side effects. If you miss a dose of Ifosym 1gm Injection and it is close to the time for your next scheduled dose, you should skip the missed dose and continue with your regular dosing schedule. It is not recommended to take a double dose to make up for a missed one.

References

  1. Baxter Corporation, [Revised on 27th Jun 2018] [Accessed on 10th Aug 2021], https://www.baxter.ca/sites/g/files/ebysai1431/files/2018-11/Ifex_EN.pdf
  2. Teva Parenteral Medicines, Inc., [Revised on Feb 2020] [Accessed on 17th Dec 2021], https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=14f535d7-4593-4cee-94fb-54ee239d95d2&type=display
  3. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976
  4. Bertram.G.Katzung, Basic and Clinical Pharmacology, Cancer Chemotherapy, 14th edition, 2017, 953.

Safety Advice

Pregnancy: unsafe Ifosym 1gm Injection is unsafe for pregnant women as it may harm the unborn baby. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 3 months after your last dose is necessary.

Lungs: Consult your doctor It is unknown whether Ifosym 1gm Injection can be used for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment

Breastfeeding: unsafe Ifosym 1gm Injection is not recommended in breastfeeding women as it may pass into the breast milk.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS