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Imated 400mg Tablet
Salt Composition: IMATINIB
- Manufacturer: THERDOSE PHARMA PVT LTD
- Pack Size: 10 TABLET(s) IN A STRIP
- Dosage Form: TABLET
- Strength: 400MG
- Prescription Required
- Storage: Store Imated 400mg tablet in room temperature (25°C) Keep the injection away from the reach of children and pets. If you forgot to take a dose, take it as soon as you remember. However, if it is nearly time for the next dose, skip the missed dose. Do not take a double dose to make up for a forgotten dose. Avoid direct contact with crushed tablets with the skin or mucous membrane. If such contact occurs, wash thoroughly.
₹473.00₹1988.44
Inclusive of all taxes
Product Introduction
Imated 400mg tablet contains the active substance imatinib. It is an antineoplastic drug that belongs to the class of tyrosine kinase inhibitors. This tablet is used in treating adults and children with chronic myeloid leukemia (CML), a form of leukaemia in which certain abnormal white blood cells start growing out of control. It is also indicated to treat Philadelphia chromosome-positive acute lymphoblastic leukaemia (Ph-positive ALL). It is also used to treat certain types of gastrointestinal stromal tumours (GIST), a type of tumour that grows in the walls of the digestive passages and may spread to other parts of the body. Imated 400mg tablet is also used to treat myelodysplastic/myeloproliferative diseases (MDS/MPD), a group of blood diseases in which some blood cells start growing out of control. It also treats hypereosinophilic syndrome (HES) and/or chronic eosinophilic leukaemia (CEL), blood diseases in which some blood cells (eosinophils) start growing out of control. This medicine is also indicated to treat dermatofibrosarcoma protuberans (DFSP), a cancer of the tissue beneath the skin in which some cells start growing abnormally. It works by inhibiting the growth of these abnormal blood cells. Do not take Imated 400mg tablet if you are allergic to imatinib or any other ingredients of this medicine. Before starting treatment, inform your doctor if you have kidney, heart, or liver problems, if you have thyroid problems, or if your thyroid gland has been removed. Notify your doctor if you have ever had or currently have a hepatitis B infection, because this medicine could cause hepatitis B to become active again. Report any symptoms of bruising, bleeding, fever, fatigue, and confusion when taking this medicine. This medicine may cause fertility problems.
Uses
Chronic myeloid leukemia (CML) Philadelphia chromosome positive acute lymphoblastic leukemia (ph-positive ALL) Myelodysplastic/myeloproliferative diseases (MDS/MPD) Hypereosinophilic syndrome (HES) Chronic eosinophilic leukemia (CEL) Dermatofibrosarcoma protuberans (DFSP) Gastrointestinal stromal tumors (GIST)
How it works
Imated 400mg tablet is a protein-tyrosine kinase inhibitor that blocks a specific abnormal protein created by a chromosomal abnormality that signals cancer cells to multiply. It inhibits the multiplication and induces cell death in abnormal cancer cells.
How to Use
Your doctor will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. Take the tablets as prescribed by your doctor. Do not break, crush, or chew the tablets. Swallow the tablet whole with a glass of water. Take this medicine with a meal to avoid stomach problems. If you are unable to swallow the tablets, you can dissolve them as per your doctor's advice.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Swelling in the face, legs, ankle, and feet Nausea, vomiting Muscle cramps and pain Diarrhea Skin rash, night sweats Tiredness, dizziness Abdominal pain Increased weight Decreased RBC and WBC cells Headache Cough, Inflammation in the nose Fever, lack of sleep Serious Heart failure GI disorders Hypothyroidism Liver failure Swelling in the body
Expert Tips
You may become more sensitive to the sun while taking Imated 400mg tablets. It is important to cover sun-exposed areas of skin and use sunscreen with a high sun protection factor after consulting with your doctor. The medicine should be administered cautiously in patients with kidney problems. This tablet may cause your body to retain water, inform your physician if you put on weight very quickly after the therapy. Your doctor will regularly do lab tests to check whether the medicine works. Do not breastfeed during the treatment with this medicine and for 15 days after your last dose.
References
- Imatinib 400mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. [revised on 2020] [cited 2023 Mar 23]. Available from: https://www.medicines.org.uk/emc/product/2297/smpc
- HIGHLIGHTS OF PRESCRIBING INFORMATION. [revised on 2016] [cited 2023 Mar 23]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021588s047lbl.pdf
- KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.
Safety Advice
Pregnancy: unsafe Imated 400mg tablet is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 15 days after your last dose is necessary.
Lungs: Consult your doctor It is unknown whether Imated 400mg tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Imated 400mg tablet because the medicine passes into the breast milk in small amounts and may harm your baby.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.