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ImatiSYM 400 Tablet

Salt Composition: IMATINIB

₹839.00₹2095.31

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

ImatiSYM 400 Tablet contains the active substance imatinib. It is an antineoplastic drug that belongs to the class tyrosine kinase inhibitor. This tablet is used in treating adults and children with chronic myeloid leukaemia (CML—a form of leukaemia in which certain abnormal white blood cells start growing out of control). It is also indicated to treat Philadelphia chromosome-positive acute lymphoblastic leukaemia (Ph-positive ALL). It is also used to treat certain types of gastrointestinal stromal tumours (GIST, a type of tumour that grows in the walls of the digestive passages and may spread to other parts of the body). ImatiSYM 400 Tablet is also used to treat myelodysplastic/myeloproliferative diseases (MDS/MPD); these are a group of blood diseases in which some blood cells start growing out of control. It also treats hypereosinophilic syndrome (HES) and/or chronic eosinophilic leukaemia (CEL); these are blood diseases in which some blood cells (eosinophils) start growing out of control. This medicine is also intended to treat dermatofibrosarcoma protuberans (DFSP), a cancer of the tissue beneath the skin in which some cells start growing abnormally. It works by inhibiting the growth of these abnormal blood cells. Do not take ImatiSYM 400 Tablet if you are allergic to imatinib or any other ingredients of this medicine. Before starting treatment, inform your doctor if you have kidney, heart, or liver problems, if you have thyroid problems, or if your thyroid gland has been removed. Notify your doctor if you have ever had or have a hepatitis B infection, as this medicine could cause the hepatitis B to become active again. Report any symptoms of bruising, bleeding, fever, fatigue, and confusion whilst taking this medicine. This medicine may cause fertility problems.

Uses

The ImatiSYM 400 Tablet is used in the treatment of the following: Chronic myeloid leukemia (CML) Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph-positive ALL) Myelodysplastic/myeloproliferative diseases (MDS/MPD) Hypereosinophilic syndrome (HES) Chronic eosinophilic leukemia (CEL) Dermatofibrosarcoma protuberans (DFSP) Gastrointestinal stromal tumors (GIST)

How it works

ImatiSYM 400 Tablet is a protein-tyrosine kinase inhibitor that blocks a specific abnormal protein created by a chromosomal abnormality that signals cancer cells to multiply. It inhibits the multiplication and induces cell death in abnormal cancer cells.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common side effects of ImatiSYM 400 Tablet are: Swelling in the face, legs, ankles, and feet Nausea, vomiting Muscle cramps and pain Diarrhea Skin rash, night sweats Tiredness, dizziness Abdominal pain Increased weight Decreased RBC and WBC cells Headache Cough, Inflammation in the nose Fever, lack of sleep Serious side effects of ImatiSYM 400 Tablet are: Heart failure GI disorders Hypothyroidism Liver failure Swelling in the body

Expert Tips

Sun sensitivity may increase while taking Imatico 400mg Tablets. Use a high-SPF sunscreen and keep exposed skin covered, as advised by your doctor. Use this medicine with caution if you have kidney problems—inform your doctor about any existing conditions. Imatico 400mg Tablets can cause fluid retention. Report any sudden weight gain to your doctor immediately. Routine lab tests may be conducted during treatment to monitor the effectiveness and safety of the medication. Avoid breastfeeding while taking this medicine and for at least 15 days after your last dose.

References

  1. 1. Imatinib 400mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. [revised on 2020] [cited 2023 Mar 23]. Available from: https://www.medicines.org.uk/emc/product/2297/smpc 2. HIGHLIGHTS OF PRESCRIBING INFORMATION. [revised on 2016] [cited 2023 Mar 23]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021588s047lbl.pdf 3. KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.

Safety Advice

Pregnancy: Unsafe ImatiSYM 400 Tablet is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnant, or planning to become pregnant. Using an effective birth control method during the treatment and for 15 days after your last dose is necessary.

Lungs: Consult Doctor

Breastfeeding: Unsafe Breastfeeding is not recommended in patients taking the ImatiSYM 400 Tablet because the medicine passes into breast milk in small amounts and may harm your baby.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS