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Inlyta 1mg Tablet

Salt Composition: AXITINIB

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Inlyta 1mg Tablet

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Inlyta 1mg Tablet is an anticancer drug belonging to the class of tyrosine kinase inhibitors, containing the active ingredient axitinib. It is used to treat advanced kidney cancer, also known as renal cell carcinoma that originates in the cells of the kidney. It is not recommended to undergo surgical procedures while on treatment with Inlyta 1mg Tablet due to the high risk of bleeding. Inform your physician before you undergo surgery or dental procedures. Seek immediate medical attention if you experience itching, vision changes, confusion, or dizziness. Inlyta Tablet may cause harm to an unborn baby. Inform your healthcare provider before beginning this treatment if you are pregnant or planning to have a baby. It is advised for both men and women to follow proper contraceptive methods during and one week after the last dose of this drug. Avoid breastfeeding while you are on treatment, as this drug can pass into breast milk and impact the growth and development of the baby. If you develop mouth sores, lose weight, or experience itchy skin, consult with your doctor. This drug is not recommended for adolescents and children under the age of 18. Contact your doctor immediately if you experience shortness of breath, chest pain, or worsening cough. During treatment, your doctor may periodically monitor your white blood cell counts, platelets, blood sugar, electrolytes, and kidney parameters to prevent serious complications. Gastrointestinal symptoms may develop during treatment, such as diarrhoea, nausea, vomiting, and constipation. Report these to your doctor right away.

Uses

The Inlyta 1mg Tablet is used in the treatment of the following: Advanced kidney cancer

How it works

It belongs to the category of tyrosine kinase inhibitors, which interferes with the growth of blood vessels inside the cancer cellS. It also acts against a protein called receptor tyrosine kinases to interrupt cell signalling, ultimately stopping the growth and spread of cancer cells.

How to Use

Your doctor will decide the dose and duration of Inylta 1mg tablet based on the disease condition. Always take this medicine as prescribed by your doctor. The recommended starting oral dose is 5 mg twice daily. Take the tablet at the same time every day, with or without food. Do not chew, crush, or break the tablet. Swallow the whole tablet with water. If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. The Inlyta side effects are: Serious Extreme tiredness and swelling Pressure or pain in the chest, arms, back, neck or jaw Breathlessness Numbness and weakness on one side of the body Difficulty speaking or communicating verbally Headache Vision changes or dizziness Serious bleeding problems like black tarry stools, bloody cough or bloody sputum Severe stomach pain High blood pressure Common Kidney problems Dehydration Hyper-active thyroid gland Sore throat Loss of appetite Joint pain Lack of energy Weight loss Constipation Mouth sores Skin itching, redness of skin and hair loss

Expert Tips

Inylta 1mg tablet can make you feel dizzy and weak. Avoid driving or operating heavy machines if you experience dizziness, confusion, or tiredness while on treatment with this drug. Grapefruit or grapefruit juice may also increase drug plasma concentrations and should be avoided. Some formulations of axitinib may contain lactose as an inactive ingredient in which the body is unable to digest lactose, a sugar found in milk and dairy products. It can cause symptoms such as bloating, and abdominal pain. If you have lactose intolerance, inform your doctor before starting this therapy. It is advised to avoid high-fiber foods and drink lots of fluids if you have severe diarrhea.

References

  1. Pfizer, [Revised on 13th Jan 2020] [Accessed on 23rd March 2023], https://www.pfizer.ca/sites/default/files/202001/INLYTA_PM_Approved_03Jan2020_E_DC.pdf
  2. Pfizer Labs, Electronic Medicines Compendium(EMC), [Revised on Mar 2021] [Accessed on 23rd March 2023], https://www.medicines.org.uk/emc/files/pil.4325.pdf
  3. Pfizer, Fact sheet, [Revised on Sep 2012] [Accessed on 23rd March 2023], https://cdn.pfizer.com/pfizercom/news/esmo/renal_cell_carcinoma_fact_sheet.pdf
  4. Annex I summary of Product Characteristics - European Medicines Agency. Available at: https://www.ema.europa.eu/en/documents/product-information/inlyta-epar-product-information_en.pdf (Accessed on March 25, 2023).
  5. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.

Safety Advice

Pregnancy: unsafe Inylta 1mg tablet is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Lungs: Consult your doctor It is not known whether Inylta 5mg tablet can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe It is unsafe to breastfeed during the treatment with Inylta 1mg tablet because it may cause harm to the baby. Please consult your doctor before breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS