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Instgra 50mg Tablet 30's

Salt Composition: DOLUTEGRAVIR

₹2719.00₹3398.61

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Instgra 50mg Tablet 30's

Categories: Infectious Disease

Conditions: Antiviral

Product Introduction

Instgra 50mg Tablet is an antiretroviral medicine in the Integrase strand transfer inhibitor class. It contains Dolutegravir as the active ingredient and is used to treat human immunodeficiency virus (HIV) infection. HIV spreads primarily through sexual contact with an infected person or through exposure to infected blood, such as by sharing injection needles. This medicine must be taken alongside other HIV treatment medicines.

This drug is contraindicated in patients with liver disease. Extra caution is necessary when administering it to patients with liver impairment due to higher drug concentration. Your doctor may need to adjust the dosage or recommend additional monitoring in these patients to ensure safety and efficacy.

During early stages of HIV treatment, some patients may experience an inflammatory response to opportunistic infections. This condition, known as immune reconstitution syndrome, can develop after starting this medicine or other antiretroviral therapies. Awareness of this possibility and monitoring for signs of worsening infections or inflammatory symptoms is necessary. Inform your healthcare provider if symptoms concern you or persist longer than expected.

Healthcare professionals must carefully monitor patients taking this drug for any signs or symptoms of skin reactions or hypersensitivity reactions, such as rash, blistering, or mucosal lesions. If a severe reaction is suspected, this medicine should be discontinued immediately and appropriate medical treatment initiated. Patients should report any skin or hypersensitivity reactions to their healthcare provider and seek immediate medical attention if they experience symptoms of a severe reaction.

Before taking this drug, inform your doctor immediately about all medicines you have been taking recently, including herbal products and supplements.

Uses

Human Immunodeficiency Virus (HIV)

How it works

Instgra 50mg Tablet works by inhibiting the enzyme integrase, thereby reducing the virus in your body. It also increases a type of white blood cell called CD4 cells which help the body fight infection.

How to Use

It is an orally available prescription drug. Your doctor will decide the dose and duration of the drug based on the disease condition and other factors. Always take Instgra 50mg Tablet as prescribed by your doctor. Take the tablet with or without food. Do not break, chew, or crush the Tablet. Swallow the whole tablet with water.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Allergic reactions (swelling, high temperature) Infection, inflammation Inflammation of the liver; liver failure Joint pain Common Depression Abnormal dreams, insomnia Itching, rash Being sick Stomach discomfort, pain Headache Diarrhea Fatigue

Expert Tips

To prevent the spread of HIV infection, avoid sharing needles or syringes, which can transmit HIV-1 infections easily. It's necessary for individuals who use injectable drugs to use sterile needles and syringes and never share them with others. Personal items like toothbrushes, razor blades, or anything with body fluids or blood should also be avoided. They should not be shared because HIV-1 can be present in blood and certain body fluids, and sharing these items could mainly transmit the virus.

References

  1. Tivicay 10mg Tablets - patient information leaflet (PIL) - (EMC). [Revised on June 2022] Available at: https://www.medicines.org.uk/emc/files/pil.10057.pdf [Accessed 22 May 2023].
  2. ViiV Healthcare, U.S. Food & Drug Administration, [Revised on June 2020] [Accessed on 22 May 2023] https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/213983s000lbl.pdf
  3. Bertram G Katzung, Basic and Clinical Pharmacology, Antiviral Agents, 14th Edition, 2017, 883.
  4. KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.

Safety Advice

Pregnancy: Consult your doctor Suppose you are pregnant or planning for pregnancy during the treatment. Please consult your doctor before taking Instgra 50mg Tablet.

Lungs: Consult your doctor It is unknown whether Instgra 50mg Tablets can be prescribed for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Instgra 50mg Tablets because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS