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Invega Sustenna 75mg Injection
Salt Composition: PALIPERIDONE
- Manufacturer: JOHNSON & JOHNSON PVT LTD
- Pack Size: 1 PREFILLED SYRINGE(s)
- Dosage Form: INJECTION
- Strength: 75MG
- Prescription Required
- Storage: Store at room temperature, between 20°C to 25°C (68°F to 77°F). Keep away from moisture, heat, and light. It should not be frozen. Keep away from children and pets.
₹8193.00₹9656.25
Inclusive of all taxes
Product Introduction
Invega Sustenna 75mg Injection contains paliperidone as its active component. It is an antipsychotic medication used to treat schizophrenia and related mental disorders such as schizoaffective disorder. It belongs to the class of drugs known as atypical antipsychotics. This medication works by affecting certain neurotransmitters in the brain, specifically dopamine and serotonin, which regulate mood, behaviour, and cognition. Schizophrenia is a chronic mental disorder characterised by delusions (false beliefs), hallucinations (false perceptions), disorganised thinking, disorganised or catatonic behaviour, and negative symptoms such as reduced emotional expression or motivation. Schizoaffective disorder is a condition that combines symptoms of schizophrenia with mood disturbances, such as depression or mania. Individuals with schizoaffective disorder experience a combination of psychotic symptoms and mood episodes. If you have a known allergy to Invega Sustenna 75mg Injection or other antipsychotic medications, you should inform your healthcare provider before starting treatment. This medication is contraindicated (not recommended) in individuals with known hypersensitivity or allergy to this medication or any of its components. It should not be used in patients with a history of severe hypersensitivity reactions to other antipsychotic medications from the same class. Additionally, it should be used cautiously in patients with a history of cardiovascular disease, seizures, or certain medical conditions. It is important to discuss your complete medical history with your healthcare provider before starting this medication or any other medication. Dosage adjustments may be necessary in patients with renal impairment. The specific age at which Invega Sustenna 75mg Injection may be considered for paediatric use can vary based on regulatory approvals and clinical guidelines in different countries.
Uses
Invega sustenna 75mg injection is used in the following: Schizophrenia treatment Schizoaffective disorder treatment
How it works
Invega sustenna 75mg injection, an atypical antipsychotic medication, primarily works by blocking dopamine receptors, particularly D2 receptors, in the brain. Reducing excessive dopamine activity helps alleviate the positive symptoms of schizophrenia, like hallucinations and delusions. Additionally, it modulates serotonin receptors, contributing to its effectiveness in managing both positive and negative symptoms. The medication's complex interactions with these neurotransmitter systems contribute to its therapeutic effects in treating schizophrenia and related conditions.
How to Use
Invega sustenna 75mg injection is administered through extended-release injection. The injection is administered by a healthcare professional as a monthly injection, gradually releasing the medication over time. The choice of administration route depends on the individual's condition, treatment plan, and the healthcare provider's recommendations.
Side Effects
Invega sustenna 75mg injection causes some side effects like all medications, although not everyone will experience them. Serious: Extrapyramidal symptoms Neuroleptic malignant syndrome (NMS) Tardive dyskinesia Cardiovascular effects Metabolic changes Blood disorders Seizures Common: Drowsiness or Sedation Dizziness Weight Gain Increased Heart Rate Dry Mouth Constipation
Expert Tips
When using Invega sustenna 75mg injection, important precautions include avoiding it in case of hypersensitivity, exercising caution if you have cardiovascular or cerebrovascular conditions, epilepsy, metabolic disorders, or a history of the neuroleptic malignant syndrome (NMS). Regular monitoring of blood glucose, potential QT interval prolongation, and neutropenia is crucial. Beware of orthostatic hypotension, and report mood changes or suicidal thoughts. Gradual discontinuation is advised, and cognitive-motor impairment may occur. Hyperprolactinemia, heat exposure, and effects on the elderly and pediatric populations should be considered. Genetic factors may impact metabolism. Use caution with alcohol, driving, and operating machinery. Communication with your healthcare provider is key to ensuring safe and effective use of this medication.
References
- Goodman & Gilmanâs, The Pharmacological Basis of Therapeutics, Anti-inflammatory, antipyretic, and analgesic agents; pharmacotherapy of psychotics and mania, 12th edition, 2011, 428.
- Janssen-Cilag International NV, Electronic medicines compendium (EMC), [Revised on 06 Oct 2021] [ Accessed on 9th August 2023], https://www.medicines.org.uk/emc/product/6816/smpc#gref
- Janssen Pharmaceuticals Inc, US Food and Drug Administration, [Revised on 06/2017] [ Accessed on 9th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/022264s023lbl.pdf
Safety Advice
Pregnancy: Consult your doctor The use of Invega sustenna 75mg injection during pregnancy should be discussed with a healthcare professional. The potential benefits and risks need to be carefully considered.
Lungs: Consult your doctor While Invega sustenna 75mg injection is primarily metabolized in the liver and does not directly affect the lungs, individuals with pre-existing respiratory conditions should inform their healthcare provider before starting the medication.
Breastfeeding: Consult your doctor The use of Invega sustenna 75mg injection during breastfeeding should be discussed with a healthcare professional.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.