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Ipoget 2gm Injection
Salt Composition: IFOSFAMIDE,MESNA
- Manufacturer: GLS PHARMA LTD
- Pack Size: 1 VIAL(s)
- Dosage Form: INJECTION
- Strength: 2GM
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Store Ipoget 2gm Injection in a refrigerator (20°C to 25°C). Do not freeze. Keep it out of reach from children.
₹675.00₹843.75
Inclusive of all taxes
Product Introduction
Ipoget 2gm Injection is an anticancer and cytoprotective medication classified as an alkylating agent and haemorrhagic cystitis inhibitor. It contains the active ingredients Ifosfamide and Mesna. The medication is indicated for treatment of bladder inflammation and cancers of soft tissue, germ cell, pancreatic and cervical origin. Mesna functions to protect against certain harmful effects of chemotherapy medications.
Ipoget 2gm Injection should not be used in patients with a known allergic reaction to this drug or any of its components. The medication may cause severe bone marrow suppression, resulting in low white blood cell count or low platelet count secondary to chemotherapy or radiation therapy. Patients who have received a live virus vaccine such as measles, mumps, rubella, or chickenpox should wait three months before commencing treatment with this drug. Caution is advised when using this medication in patients with severe kidney or liver disease.
Inform your doctor of all other medications, over-the-counter medicines, or herbal products being taken. Your doctor will assess the risk of drug interaction. Ipoget 2gm Injection is contraindicated in pregnancy as it may cause harm to the fetus. A pregnancy test will be conducted before commencing treatment. Effective birth control methods should be discussed with your doctor and used for at least two weeks following the final dose. Breastfeeding should be avoided during treatment with this medication as it may pass into breast milk in small quantities.
Uses
Ipoget 2gm Injection is used in the treatment of the following: Hemorrhagic cystitis (bladder inflammation) Soft tissue cancer Germ cell cancer Pancreatic cancer Cervical cancer
How it works
The Ipoget 2gm Injection works by damaging the DNA in cancer cells, which leads to cell death and slows the growth and spread of cancer. Mostly, this involves the formation of reactive metabolites in the liver, which are then transported to cancer cells in the body. These metabolites react with the DNA in the cancer cells, causing cross-links and breaks in the DNA strands. This interferes with the replication and transcription of DNA, leading to cell death.
How to Use
Ipoget 2gm Injection will be given to you by a doctor or nurse in a hospital or clinic setting trained in cancer chemotherapy. It is given as an intravenous infusion drip (into your vein). Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity, body weight, and other factors.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious side effects of Ipoget 2gm Injection are: Immune system suppression Low levels of RBC, WBC and platelets in the blood Bone marrow suppression Nerve toxicity Urinary problems Lung problems Kidney problem Rash Hypersensitivity reactions Common side effects of Ipoget 2gm Injection are: Hair loss Fever Phlebitis Liver toxicity Infections
Expert Tips
The Ipoget 2gm Injection may cause severe birth defects if taken during pregnancy. Female patients with reproductive potential should use effective contraception during the treatment. Male patients with female partners with reproductive potential should use effective birth control methods during the treatment and for at least 5 months after their last dose. Do not breastfeed during treatment with this injection. Your doctor may advise you to take certain tests to check for the effectiveness of the therapy. Ipoget 2gm Injection may cause dizziness, drowsiness, or blurred vision, so it is important to avoid driving. It's important to avoid consuming grapefruit or grapefruit juice while taking this injection because this can lead to increased levels of the drug in your body and a higher risk of side effects. If you miss a dose of Ipoget 2gm Injection and it is close to the time for your next scheduled dose, you should skip the missed dose and continue with your regular dosing schedule. It is not recommended to take a double dose to make up for a missed one.
References
- Baxter Corporation, [Revised on 27th Jun 2018] [Accessed on 10th Aug 2021], https://www.baxter.ca/sites/g/files/ebysai1431/files/2018-11/Ifex_EN.pdf
- Teva Parenteral Medicines, Inc., [Revised on Feb 2020] [Accessed on 17th Dec 2021], https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=14f535d7-4593-4cee-94fb-54ee239d95d2&type=display
- Boehringer-Ingelheim, Mesna [Revised on March 2014] [ Accessed on 06 April 2023], https://docs.boehringer-ingelheim.com/Prescribing%20Information/PIs/Ben%20Venue_Bedford%20Labs/55390-045-01%20MSN%201G/5539004501
- Edward Chu, Cancer Chemotherapy, Langeâs Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976
- Bertram.G.Katzung, Basic and Clinical Pharmacology, Cancer Chemotherapy, 14th edition, 2017, 953.
Safety Advice
Pregnancy: unsafe Ipoget 2gm Injection is unsafe for pregnant women as it may harm the unborn baby. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 3 months after your last dose is necessary.
Lungs: Consult your doctor It is unknown whether Ipoget 2gm Injection can be used for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: unsafe Ipoget 2gm Injection is not recommended in breastfeeding women as it may pass into the breast milk.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.