Irinozee 40mg Injection

Irinozee 40mg Injection is an anti-cancer medicine belonging to the class of cytostatics. It contains the active ingredient Irinotecan hydrochloride trihydrate. The injection is indicated for advanced colon cancer and rectal cancer in adults. It may be administered as monotherapy or in combination with other chemotherapeutic agents. Colon and rectal cancer prevalence is higher in age groups above 50 years and is associated with genetic and environmental factors. Myelosuppression (bone marrow suppression resulting in reduced red blood cells, white blood cells, and platelets) and diarrhea are the most frequently reported adverse effects. Additional common side effects include nausea, vomiting, abdominal pain, constipation, anaemia, pain, fatigue, fever, infections including sepsis, abnormal bilirubin levels, alopecia, and weight loss. Inform your doctor if these side effects are troublesome or persistent. Notify your doctor if you have chronic inflammatory bowel disease, bowel obstruction, or have received any live vaccines. Disclose any allergy to Irinotecan and its components to your physician. Before commencing treatment, inform your physician of liver problems or jaundice, kidney disease, cardiac problems, asthma, hypertension, hypercholesterolaemia, or severe diarrhea. Report smoking history or prior radiation therapy to your healthcare provider. Discuss all concurrent medications, herbal preparations, and supplements with your healthcare provider. Both males and females must practise effective contraception during treatment to prevent pregnancy. Your physician will conduct blood tests before and during treatment to monitor effects on blood cell counts and blood chemistry parameters.

Treatment of metastatic cancer of the colon and rectum (large intestine).

Irinozee 40mg Injection works by converting its active metabolite with the help of liver enzymes and inhibits the Topoisomerase I enzyme. This causes damage to the DNA synthesis and its replication, thus preventing the cancer cells from growing and spreading.

Take this medicine exactly as prescribed. Your healthcare professional administers it into your vein. Do not self-administer. Your physician will recommend a DNA test before taking this medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Early and late diarrhea Allergic reactions Kidney impairment Lung problems Low levels of RBC, WBC, and platelets in the blood Common Nausea, vomiting, abdominal pain Constipation Diarrhea Anemia Pain Fatigue Fever, infections including sepsis Abnormal bilirubin levels Hair loss Weight loss

This injection should be taken cautiously in patients with kidney disease or who have undergone dialysis. Diarrhea is the first sign of Irinozee 40mg Injection. It may be serious if diarrhea starts more than 24 hours after administration of this medication. It should be treated immediately and kept under close supervision. If left untreated, it could lead to dehydration and serious chemical imbalances, which can be life-threatening. Try to avoid laxatives and stool softeners while taking Irinozee 40mg Injection. Drink large amounts of water and rehydration fluids immediately. Take antidiarrheal treatment like loperamide. Notify your doctor if you experience any serious side effects. Contact your doctor for more information. Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose.