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Iritero 40mg Injection
Salt Composition: IRINOTECAN
- Manufacturer: HETERO HEALTHCARE LTD
- Pack Size: 1 VIAL(s)
- Dosage Form: INJECTION
- Strength: 40MG
- Prescription Required
- Storage: Do not freeze. Store protected from light at a temperature not exceeding 25°C. Keep this medicine away from the sight and reach of children.
₹444.00₹724.69
Inclusive of all taxes
Product Introduction
Iritero 40 mg Injection is an anti-cancer medicine belonging to the group of cytostatics. The active ingredient is Irinotecan hydrochloride trihydrate. It is indicated for advanced colon cancer and rectal cancer in adults. It may be prescribed alone or in combination with other chemotherapeutic agents. Colon and rectal cancer is prevalent in age groups above 50 years and is further triggered by genetic and environmental factors. Myelosuppression (bone marrow suppression leading to low levels of red blood cells, white blood cells, and platelets in the blood) and diarrhoea are the most common adverse effects of this medication. Other common side effects of Iritero 40 mg Injection include nausea, vomiting, abdominal pain, constipation, anaemia, pain, fatigue, fever, infections including sepsis, abnormal bilirubin levels, hair loss, and weight loss. Inform your doctor if these side effects disturb or persist. Inform your physician if you are allergic to Iritero 40 mg Injection and its ingredients. Before starting treatment, let your physician know if you have liver problems or jaundice, kidney and heart problems, asthma, high blood pressure or high cholesterol, or severe diarrhoea. If you are smoking or have ever received radiation therapy, report to your healthcare provider. Consult your healthcare provider if you take other medicines, herbs, and supplements. Effective contraception by males and females during treatment is important to avoid pregnancy. Your physician will perform blood tests during and before treatment to check for the effects of the medicine on blood counts and blood chemistry.
Uses
Treatment of metastatic cancer of the colon and rectum (large intestine).
How it works
Iritero 40 mg Injection works by converting its active metabolite with the help of liver enzymes and inhibits the Topoisomerase I enzyme. This causes damage to the DNA synthesis and its replication, thus preventing the cancer cells from growing and spreading.
How to Use
Take this medicine exactly as prescribed. Your healthcare professional administers it into your vein. Do not self-administer. Your physician will recommend a DNA test before taking this medicine. The dose depends on your age, size, and medical condition.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Early and late diarrhea Allergic reactions Kidney impairment Lung problems Low levels of RBC, WBC, and platelets in the blood Common: Nausea, vomiting, abdominal pain Constipation Diarrhea Anemia Pain Fatigue Fever, infections including sepsis Abnormal bilirubin levels Hair loss Weight loss
Expert Tips
Diarrhea is the first sign of Iritero 40 mg Injection. It may be serious if diarrhea starts more than 24 hours after administration of this medication. It should be treated immediately and kept under close supervision. If left untreated, it could lead to dehydration and serious chemical imbalances, which can be life-threatening. Try to avoid laxatives and stool softeners while taking this medicine. Drink large amounts of water and rehydration fluids immediately. Take antidiarrheal treatment like loperamide.
References
- Accord Healthcare Limited, Electronic Medicines Compendium (EMC), [Revised on June 2022] [Accessed on 24 Nov 2022], https://www.medicines.org.uk/emc/files/pil.7318.pdf
- Pharmacia & Upjohn Co, US Food & Drug Administration, [Revised on Dec 2014] [Accessed on 24 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020571s048lbl.pdf
- I.D. Penman, C.W. Lees, Alimentary Tract and Pancreatic Disease, Davidsonâs Principles and Practice of Medicine, 22nd Edition, 2014, 837-920.
- Edward Chu, Cancer Chemotherapy, Langeâs Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
Safety Advice
Pregnancy: unsafe Take this medicine exactly as prescribed. Your healthcare professional administers it into your vein. Do not self-administer. Your physician will recommend a DNA test before taking this medicine. The dose depends on your age, size, and medical condition.
Lungs: Consult your doctor It is unknown whether it is safe to administer Iritero 40 mg Injection in patients with lung disorders. Please consult your doctor for more advice.
Breastfeeding: unsafe It is unsafe to use during breastfeeding as Iritero 40 mg Injection, and its metabolites are found in human milk. It must be discontinued for the duration of therapy. Consult your doctor for advice.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.