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Irnocam 100mg Injection
Salt Composition: IRINOTECAN
- Manufacturer: DR REDDY'S LABORATORIES LTD
- Pack Size: 1 VIAL(s) OF 5ML
- Dosage Form: INJECTION
- Strength: 100MG
- Prescription Required
- Storage: Do not freeze. Store protected from light at a temperature not exceeding 25°C. Keep this medicine away from the sight and reach of children.
₹1317.00₹1646.06
Inclusive of all taxes
Product Introduction
Irnocam 100 mg Injection is an anti-cancer medicine classified as a cytostatic agent. It contains the active ingredient Irinotecan hydrochloride trihydrate. The injection is indicated for advanced colon cancer and rectal cancer in adults, and may be prescribed as monotherapy or in combination with other chemotherapeutic agents. Colorectal cancer occurs more frequently in age groups above 50 years and is influenced by genetic and environmental factors.
Myelosuppression (bone marrow suppression resulting in reduced red blood cells, white blood cells, and platelets) and diarrhoea are the most frequently reported adverse effects. Other common side effects include nausea, vomiting, abdominal pain, constipation, anaemia, pain, fatigue, fever, infections including sepsis, abnormal bilirubin levels, alopecia, and weight loss. Notify your doctor if these side effects occur or persist.
Inform your physician if you have an allergy to Irnocam 100 mg Injection or any of its ingredients. Before beginning treatment, disclose to your doctor if you have liver disease or jaundice, kidney and cardiac problems, asthma, hypertension, hypercholesterolaemia, or severe diarrhoea. Report any history of smoking or prior radiation therapy to your healthcare provider. Discuss all other medications, herbal products, and supplements you are taking with your physician.
Effective contraception by both males and females during treatment is essential to prevent pregnancy. Your doctor will arrange blood tests before and during treatment to monitor the effects of the medication on blood cell counts and blood chemistry parameters.
Uses
Treatment of metastatic cancer of the colon and rectum (large intestine).
How it works
Irnocam 100 mg Injection works by converting its active metabolite with the help of liver enzymes and inhibits the Topoisomerase I enzyme. This causes damage to the DNA synthesis and its replication, thus preventing the cancer cells from growing and spreading.
How to Use
Take this medicine exactly as prescribed. Your healthcare professional administers it into your vein. Do not self-administer. Your physician will recommend a DNA test before taking this medicine. The dose depends on your age, size, and medical condition.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Early and late diarrhea Allergic reactions Kidney impairment Lung problems Low levels of RBC, WBC, and platelets in the blood Common: Nausea, vomiting, abdominal pain Constipation Diarrhea Anemia Pain Fatigue Fever, infections including sepsis Abnormal bilirubin levels Hair loss Weight loss
Expert Tips
Diarrhea is the first sign of Irnocam 100 mg Injection. It may be serious if diarrhea starts more than 24 hours after administration of this medication. It should be treated immediately and kept under close supervision. If left untreated, it could lead to dehydration and serious chemical imbalances, which can be life-threatening. Try to avoid laxatives and stool softeners while taking this medicine. Drink large amounts of water and rehydration fluids immediately. Take antidiarrheal treatment like loperamide.
References
- Accord Healthcare Limited, Electronic Medicines Compendium (EMC), [Revised on June 2022] [Accessed on 24 Nov 2022], https://www.medicines.org.uk/emc/files/pil.7318.pdf
- Pharmacia & Upjohn Co, US Food & Drug Administration, [Revised on Dec 2014] [Accessed on 24 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020571s048lbl.pdf
- I.D. Penman, C.W. Lees, Alimentary Tract and Pancreatic Disease, Davidsonâs Principles and Practice of Medicine, 22nd Edition, 2014, 837-920.
- Edward Chu, Cancer Chemotherapy, Langeâs Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
Safety Advice
Pregnancy: unsafe Take this medicine exactly as prescribed. Your healthcare professional administers it into your vein. Do not self-administer. Your physician will recommend a DNA test before taking this medicine. The dose depends on your age, size, and medical condition.
Lungs: Consult your doctor It is unknown whether it is safe to administer Irnocam 100 mg Injection in patients with lung disorders. Please consult your doctor for more advice.
Breastfeeding: unsafe It is unsafe to use during breastfeeding as Irnocam 100 mg Injection, and its metabolites are found in human milk. It must be discontinued for the duration of therapy. Consult your doctor for advice.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.