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Isogen 125mg Capsule

Salt Composition: PALBOCICLIB

₹5785.00₹25150.78

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Isogen 125mg Capsule

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Isogen 125mg Capsule contains palbociclib, a cyclin-dependent kinase inhibitor used in anticancer therapy. It is indicated for the treatment of hormone receptor-positive, human epidermal growth factor 2 negative advanced or metastatic breast cancer. The medication is administered in combination with other anticancer agents.

Common side effects associated with Isogen 125mg include nausea, vomiting, diarrhoea, fatigue, alopecia, dry skin, rash, infections, epistaxis, decreased appetite, low blood cell counts, oedema of lips and mouth, taste alterations, dry eye, blurred vision, and increased lacrimation. Inform your doctor if these side effects persist or cause concern.

Notify your healthcare provider of any allergy to palbociclib or its components. Prior to initiating treatment, disclose to your doctor any existing conditions including signs of infection (fever, chills, sore throat), liver impairment, renal impairment, or sugar intolerance. Seek immediate medical attention if you experience dry cough, chest pain, or breathing difficulty, as these may indicate pulmonary inflammation.

Inform your physician of all concurrent medications, including supplements and herbal preparations, before starting this treatment. Effective contraception is necessary during treatment and for at least three weeks following the final dose. Use in patients under 18 years of age is not recommended.

Uses

Isogen capsule uses are: Treatment of hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer .

How it works

Isogen 125 mg works by blocking the protein called cyclin-dependent kinases 4 and 6, which are vital for the division and growth of cells. By blocking these proteins, this medication slows the growth and prevents the cancer cells from spreading.

How to Use

Take Isogen 125 mg exactly as prescribed by your doctor. Take this medication once a day at the same time with food. Swallow this capsule as a whole with a glass of water. Avoid crushing, breaking, or chewing the capsule.

Side Effects

isogen side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious: Blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising) Lung inflammation (chest pain, dry cough, or difficulty breathing) Common: Tiredness Hair loss Dry skin, rash Infections Low blood cell counts Decreased of appetite Nausea, vomiting Diarrhea Swelling of lips and mouth Changes in taste Nose bleed Dry eye, blurred vision, increased tearing

References

  1. Pfizer Limited, Electronic medicines compendium (emc), [Revised on June 2021] [ Accessed on 26 Nov 2022], https://www.medicines.org.uk/emc/files/pil.4449.pdf
  2. Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf
  3. Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022; https://pubmed.ncbi.nlm.nih.gov/26324355/
  4. Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022; https://labeling.pfizer.com/ShowLabeling.aspx?id=14029

Safety Advice

Pregnancy: unsafe It is not recommended to take Isogen 125 mg during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.

Lungs: Consult your doctor It is not unknown whether Isogen 125 mg can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Taking Isogen 125 mg while breastfeeding is not recommended as it is not known whether it passes into the breast milk.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS