Home › Products › Cardiology › Izirize Injection 1.5ml
Izirize Injection 1.5ml
Salt Composition: INCLISIRAN
- Manufacturer: JB CHEMICALS
- Pack Size: 1 PREFILLED SYRINGE(s) OF 1.5ML
- Dosage Form: INJECTION
- Strength: 284MG
- Prescription Required
- Storage: Izirize Injection 1.5ml should be stored at room temperature, between 20°C to 25°C (68°F to 77°F). Protected from light. Keep it in its original packaging until it is ready to be used. Keep out of the reach of children and pets. Should be disposed of properly.
₹97322.00₹105580.36
Inclusive of all taxes
Product Introduction
Izirize Injection 1.5ml contains inclisiran as its active ingredient and belongs to the class of proprotein convertase subtilisin kexin type-9 (PCSK-9) inhibitors. It is the first and only small interfering RNA (siRNA) therapy developed to lower low-density lipoprotein cholesterol. This medication is used to reduce low-density lipoprotein levels and is prescribed alongside statin therapy and dietary modifications in the management of patients with primary hypercholesterolaemia.
Do not use this medication if you are allergic to inclisiran or any component of the formulation. Use during pregnancy and breastfeeding is not recommended; consult your physician for guidance. This medication is not recommended for children and adolescents below 18 years of age.
You should be taking a statin and following a cholesterol-lowering diet before starting this therapy. Continue taking your statin and adhering to the prescribed diet throughout the duration of treatment with Izirize Injection 1.5ml. Do not discontinue this medicine without consulting your doctor.
Inform your doctor if you have kidney disorders, respiratory problems, liver disorders, cardiac conditions, or sugar intolerance prior to commencing treatment. Notify your physician or pharmacist of all medications you are currently taking, have recently taken, or plan to take, including over-the-counter medicines and herbal preparations.
Uses
Combination to other statin therapy and diet for treating primary hyperlipidemia [heterozygous familial hypercholesterolemia].
How it works
Izirize Injection 1.5ml is a small interfering RNA (siRNA) molecule that interferes with the production of PCSK9 protein in the liver. By inhibiting PCSK9 synthesis, Izirize Injection 1.5ml increases the number of LDL receptors on liver cells, promoting the clearance of LDL cholesterol from the blood. This mechanism ultimately leads to lower LDL cholesterol levels in the bloodstream, helping to reduce the risk of cardiovascular events such as heart attack and stroke.
Side Effects
Like all medications, Izirize Injection 1.5ml can cause side effects, although not everyone who takes it will experience them. Common: Injection site reactions like redness, rash and pain Arthralgia Bronchitis Fever Chills Headache.
Expert Tips
Eating a balanced diet low in saturated and trans fats. Exercising regularly. Maintaining a healthy weight. Quitting smoking. Do not stop your regular statin medications and continue following a proper diet, as Izirize Injection 1.5ml is only effective when combined with these therapies. Do not discontinue this drug without the advice of a healthcare professional, even if symptoms improve. Follow your doctor’s advice and routinely check your cholesterol levels to: Monitor the efficacy of Izirize Injection 1.5ml Allow timely adjustments to your treatment regimen if required.
References
- Novartis Pharmaceuticals Corporation , US Food and Drug Administration, [ Revised on July 2023] [ Accessed on 05-03-2024 ], https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/214012s009lbl.pdf
- Novartis Pharmaceuticals UK Ltd. Electronic medicines compendium (emc), [ Revised on November 2022] [ Accessed on 05-03-2024], https://www.medicines.org.uk/emc/files/pil.12039.pdf
- Leqvio, Novartis Pharmaceuticals Ltd, https://www.leqvio.com/
Safety Advice
Pregnancy: Consult Your Doctor It is recommended to avoid this medication during pregnancy as Izirize Injection 1.5ml is unsafe during pregnancy as it can cause fetal harm. It is advised to inform your physician if you are pregnant or think you may be pregnant before starting the treatment.
Lungs: Consult Your Doctor It is unknown whether Izirize Injection 1.5ml Injection is safe for patients with lung problems. Consult your doctor if you have lung disease before starting the treatment.
Breastfeeding: Consult Your Doctor It is unknown whether Izirize Injection 1.5ml is excreted in human milk. It is advised to consult your doctor before taking Izirize Injection 1.5ml. Your doctor may prescribe this if the benefits of the drug outweighs the risks involved.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.