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Jakauto 5mg Tablet

Salt Composition: TOFACITINIB

₹140.00₹154.68

Inclusive of all taxes

Categories: Rheumatology

Conditions: Arthritis

Product Introduction

Jakauto 5mg tablet contains tofacitinib, a disease-modifying antirheumatoid drug belonging to the class of immunomodulators. It is used alone or in combination with other medications to treat rheumatoid arthritis (a condition in which the body attacks its joints, causing pain, swelling, and loss of function) in adults who are unable to tolerate or do not respond to other medications. It is also used to treat psoriatic arthritis (a condition that causes joint pain and swelling, and scales on the skin). Jakauto 5mg tablet is also indicated for treating adult patients with moderately to severely active ulcerative colitis. Other uses include ankylosing spondylitis (inflammatory disease of the spine) and active polyarticular juvenile idiopathic arthritis, a long-term disease that causes pain and swelling of the joints in patients 2 years of age and older. The medicine works by decreasing the activity of the immune system.

Inform your physician if you have severe blood infection, active tuberculosis, or liver problems. Notify your doctor if you have had or currently have hepatitis B infection, as this medicine could cause hepatitis B to become active again. Do not take Jakauto 5mg tablet if you are allergic to tofacitinib or any other ingredients of this medicine.

Inform your healthcare professional if you develop any symptoms of infection, such as fever, sweating, chills, muscle aches, cough, shortness of breath, weight loss, skin sores, difficulty or pain when swallowing, diarrhoea, or stomach pain.

Before initiating treatment, inform your physician if you have kidney, heart, lung, or liver problems; a history of tuberculosis; high blood pressure; high cholesterol; or if you are a current or past smoker.

Uses

Rheumatoid arthritis Psoriatic arthritis Ankylosing spondylitis Ulcerative colitis Polyarticular juvenile idiopathic arthritis Juvenile psoriatic arthritis

How it works

Jakauto 5mg tablet is a disease-modifying anti-rheumatic drug (DMARD) in the category of Janus Kinase Inhibitors. Janus kinase is a type of enzyme (tyrosine kinase) involved in the signaling of cytokine receptors. It works by inhibiting Janus kinases and interferes with the transcription of genes involved in cell growth and differentiation.

How to Use

Your doctor will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. Take the tablets as prescribed by your doctor. Do not break, crush, or chew the tablets. Swallow the tablet whole with a glass of water. Take the tablet with or without food.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Increased cholesterol levels Headache Painful urination Inflammation of the nose Cough Shortness of breath Diarrhea Skin rashes Serious Lung cancer White blood cell cancer Heart attack Fever and chills Blood in the stool Stomach pain or abdominal pain Skin blisters

Expert Tips

This medicine may interfere with vaccines, inform your physician about your vaccination history. This medicine may impair fertility; talk to your doctor before taking this medicine. Your doctor will regularly do lab tests to check whether the medicine is working. Do not breastfeed during the treatment with this medicine and for at least 36 hours after your last dose. This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury.

References

  1. XELJANZ 5 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk. [cited 2023 Mar 25]. Available from: https://www.medicines.org.uk/emc/product/2500/smpc
  2. HIGHLIGHTS OF PRESCRIBING INFORMATION - Tofacitinib. [revised on 2018] [cited 2023 Mar 25]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/203214s018lbl.pdf
  3. ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS - Tofacitinib. [cited 2023 Mar 25]. Available from: https://www.ema.europa.eu/en/documents/product-information/xeljanz-epar-product-information_en.pdf

Safety Advice

Pregnancy: unsafe Jakauto 5mg tablet is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for at least 4 weeks after your last dose is necessary.

Lungs: Consult your doctor It is unknown whether Jakauto 5mg tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Jakauto 5mg tablet because the medicine passes into the breast milk in small amounts and may harm your baby.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS