Jakavi 10mg Tablet

Jakavi 10mg Tablet contains ruxolitinib as the active ingredient. It is an anticancer agent belonging to the class of kinase inhibitors. It is used to treat myelofibrosis, a rare type of bone marrow cancer that causes decreased blood cell production. It is also used to treat polycythemia vera, a type of blood cancer where the body produces excessive red blood cells, in patients who are resistant to or cannot be treated successfully with other medication such as hydroxyurea. The medicine is also indicated for acute graft versus host disease, a complication of transplant procedures in which diseased bone marrow is replaced with healthy bone marrow, previously treated unsuccessfully with steroid medications in adults and children aged 12 years and above. It is also used for chronic graft versus host disease in adults and children aged 12 years and older who were treated unsuccessfully with one or two other systemic treatments. Jakavi 10mg Tablet works by blocking the signals that cause cancer cells to multiply. Do not take this medicine if you are allergic to ruxolitinib or any other ingredients in this medicine. Inform your physician if you have or had tuberculosis, hepatitis B or C, liver disease, or kidney problems. The most common adverse effects are dizziness, reduced blood counts, bruising, bleeding, headache, and facial and body swelling. Notify your physician if you are on dialysis.

Myelofibrosis Polycythemia vera Acute-graft-versus host disease Chronic-graft-versus host disease

Ruxolitinib, a kinase inhibitor, inhibits dysregulated Janus Associated Kinase (JAK) 1 and JAK2 signaling associated with myelofibrosis and polycythemia vera. By blocking certain enzymes, this medicine can reduce the serious risk of blood or vascular complications in myelofibrosis and polycythemia vera. In GVHD, it reduces the signs and symptoms, improving the disease and survival of transplanted cells.

Your doctor will decide the dose and duration of Jakavi 10mg Tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time, with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Severe infections like hepatitis B Anemia Bleeding Common Low red and white blood cell counts Low platelet counts Dizziness, headache Bruising Diarrhea Infections including viral infection Swelling in the face and body Fatigue or tiredness

You should continue taking this tablet until your doctor says since it is a long term treatment. Do not stop taking Jakavi 10mg Tablet or reduce its dose without consulting a physician. Inform your physician if you get any infection or symptoms of bleeding during the treatment. This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Inform your doctor if you are a smoker or a past smoker.