Jakavi 20mg Tablet

Jakavi 20mg tablet contains ruxolitinib, a kinase inhibitor used in the treatment of certain blood cancers and bone marrow disorders. It is indicated for myelofibrosis, a rare bone marrow cancer characterised by decreased blood cell production. The tablet is also used to treat polycythemia vera, a blood cancer in which the body produces excess red blood cells, in patients with resistance to hydroxyurea or in whom hydroxyurea treatment has been unsuccessful. Jakavi is indicated for acute graft versus host disease, a complication following bone marrow transplantation, in adults and children aged 12 years and above when previous steroid therapy has been unsuccessful. It is also used for chronic graft versus host disease in adults and children aged 12 years and older who have not responded adequately to 1 or 2 prior systemic treatments. The medication works by inhibiting cellular signalling pathways that promote cancer cell proliferation.

Do not take Jakavi 20mg tablet if you are allergic to ruxolitinib or any other components of this medicine. Inform your physician if you have a history of tuberculosis, hepatitis B or C, liver disease, or kidney problems. The most frequently reported adverse effects include dizziness, reduced blood counts, bruising, bleeding, headache, and facial and body swelling. Notify your physician if you are undergoing dialysis.

Myelofibrosis Polycythemia vera Acute-graft-versus host disease Chronic-graft-versus host disease

Ruxolitinib, a kinase inhibitor, inhibits dysregulated Janus Associated Kinase (JAK) 1 and JAK2 signalling associated with myelofibrosis and polycythemia vera. By blocking certain enzymes, this medicine can reduce the serious risk of blood or vascular complications in myelofibrosis and polycythemia vera. In GvHD, it reduces the signs and symptoms, improving the disease and survival of transplanted cells.

Your doctor will decide the dose and duration of Jakavi 20mg tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time, with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Low red and white blood cell counts Low platelet counts Dizziness, headache Bruising Diarrhea Infections including viral infection Swelling in the face and body Fatigue or tiredness Serious Severe infections like hepatitis B Anemia Bleeding

You should continue taking this tablet until your doctor says since, it is a long-term treatment. Do not stop taking Jakavi 20mg tablet or reduce its dose without consulting a physician. Inform your physician if you get any infection or symptoms of bleeding during the treatment. This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Inform your doctor if you are a smoker or a past smoker.