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Janumet 50/500mg Tablet

Salt Composition: SITAGLIPTIN,METFORMIN

₹288.00₹351.56

Inclusive of all taxes

Categories: Others

Conditions: Diabetes Mellitus

Product Introduction

Janumet 50/500mg Tablet is an oral antidiabetic medicine that combines Sitagliptin and Metformin to help manage type 2 diabetes mellitus. This combination works by improving the body's response to insulin, reducing glucose production in the liver, and increasing insulin release after meals, helping to maintain healthy blood sugar levels. Janumet 50/500mg Tablet is prescribed alongside a balanced diet and regular exercise to achieve better glycaemic control in adults with type 2 diabetes.

Unlike some diabetes medications, Janumet 50/500mg Tablet is generally weight-neutral and may even support modest weight loss in certain individuals. It also has a lower risk of causing hypoglycaemia (low blood sugar) when taken as directed, especially if it is not used together with insulin or sulfonylureas. Some clinical studies have also suggested potential cardiovascular benefits, including a reduced risk of heart-related complications such as heart attack and stroke in appropriate patients with type 2 diabetes.

Do not take Janumet 50/500mg Tablet if you are allergic to Sitagliptin, Metformin, or any of its ingredients. This medicine is not recommended for people with severe kidney impairment, end-stage kidney disease, or an estimated glomerular filtration rate (eGFR) below 30 mL/min/1.73 m², as it may increase the risk of lactic acidosis, a rare but serious medical condition. It should also be avoided in individuals with metabolic acidosis, including diabetic ketoacidosis (DKA).

Before starting treatment, inform your healthcare provider if you have a history of heart failure, liver disease, kidney disease, or any other chronic medical condition. Older adults may require closer monitoring because age-related changes in kidney and liver function can affect how the medicine works and may require dosage adjustments.

Janumet 50/500mg Tablet is not recommended for children, as its safety and effectiveness in the paediatric population have not been established. Always take this medicine exactly as prescribed by your doctor and attend regular follow-up appointments to monitor your blood sugar levels and overall health.

Uses

Janumet 50mg/500mg uses are: Type 2 diabetes management Blood sugar control Weight management Cardiovascular health

How it works

Tab Janumet 50mg/500mg works by combining its two active ingredients, which act synergistically. Sitagliptin enhances insulin release and reduces glucagon levels, while metformin decreases liver glucose production and enhances peripheral glucose uptake. Together, they help control blood sugar levels in individuals with type 2 diabetes.

How to Use

Janumet 50mg/500mg can be administered orally. Follow the prescribed dosage and any additional instructions provided by the healthcare professional for the safe and effective use of janumet 50mg/500mg tablet.

Side Effects

Janumet 50mg/500 side effects are: Serious Lactic Acidosis Pancreatitis Hypoglycemia Common Diarrhea Nausea Vomiting Gas Stomach upset or pain

Expert Tips

Watch out for any signs of allergies like rash or swelling after taking janumet 50/500mg tablet. Regularly check how well your kidneys and liver are working. If you have any heart problems, be careful while using this medication. Pay attention to signs like feeling shaky or dizzy, which might mean your blood sugar is too low. Be aware of any new infections or if you feel sick. If you are pregnant or breastfeeding, talk to your doctor before taking it. Tell your doctor if you have any surgeries coming up. It is better to avoid too much alcohol while taking this medication. Make sure to drink enough water, especially if you are sick. Long-term use of this medication might affect your vitamin levels, so ask your doctor about it. Along with taking the medication, maintain a healthy diet and stay physically active as your doctor advises. Manage your stress levels and get enough rest to support your overall well-being.

References

  1. Merck Sharp & Dohme (UK) Limited, Electronic Medicines Compendium (EMC), [Revised on February 2022] [Accessed on 27th Oct 2023], https://www.medicines.org.uk/emc/files/pil.564.pdf
  2. Merck Sharp & Dohme Corp., U.S. Food and Drug Administration, [Accessed on 27th Oct 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022044s022lbl.pdf
  3. KD Tripathi, Essentials of Medical Pharmacology, Hormones, and Related Drugs, 7th edition, 2013, 274-276

Safety Advice

Pregnancy: Consult your doctor Janumet 50mg/500mg tablets are not recommended during pregnancy. Discuss the potential risks and benefits with a healthcare provider before using it during pregnancy.

Lungs: Consult your doctor Consult your healthcare provider if you have a history of lung conditions before using the janumet 50mg/500mg tablet.

Breastfeeding: Consult your doctor Janumet 50mg/500mg tablets may not be recommended for breastfeeding mothers. Consult a healthcare provider for guidance on using this medication while breastfeeding and to know about janumet tablet uses.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS