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Jectophen 1.0gm Injection

Salt Composition: CHLORAMPHENICOL SODIUM

₹160.00₹205.31

Inclusive of all taxes

Categories: Infectious Disease

Conditions: Antibacterials

Product Introduction

Jectophen 1.0gm Injection contains chloramphenicol sodium succinate, a broad-spectrum antibacterial agent. It is indicated for severe systemic bacterial infections, including typhoid, meningitis, and other infections. This injection is typically administered when prior antibiotic therapy has been ineffective, when oral chloramphenicol is not feasible, or when high blood concentrations of the medication are required.

Do not use this injection if you are allergic to chloramphenicol. Avoid use during pregnancy or while breastfeeding without medical consultation. Inform your healthcare provider if you have a history of kidney disease, liver disease, or are concurrently taking medications associated with bone marrow depression. Similarly, report any current cold, viral influenza, or throat infection. Disclose if you have recently received vaccination or have one scheduled.

Jectophen 1.0gm Injection carries risk of bone marrow suppression and bleeding disorders, including anaemia (reduction in red blood cells), leucopenia (decrease in white blood cells), and thrombocytopenia (decrease in platelets). These conditions may compromise immune function and in some cases progress to leukaemia. Inform your healthcare provider of any prior history of these disorders before commencing treatment. Provide your doctor with a complete medical history and list of current medications.

Uses

Serious bacterial infections

How it works

Jectophen 1.0gm injection works by inhibiting bacterial protein synthesis by disrupting the transfer of activated amino acids from soluble RNA to ribosomes. This interference prevents bacterial growth and multiplication, resulting in a bacteriostatic effect.

How to Use

This medicine is given only in a hospital setup by a healthcare provider. It is infused directly into your veins by your healthcare provider. Your physician will decide the dosage and frequency of this injection based on the severity of your disease and other factors.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious Severe allergic reactions such as redness and itching Grey baby syndrome (marked by a swollen belly, a sudden drop in blood pressure, and a pale grayish color of the skin) White blood cell counts can also drop, increasing the chance of infections and fever Anemia (a low red blood cell count) leaves you tired and lethargic. Common Thrombocytopenia (decrease in platelets) Dry mouth, Nausea, and vomiting Headache and Depression Numbness, tingling, pain or muscle weakness Blurring, inflammation, or temporary loss of vision Immune suppression and development of infections

Expert Tips

During the treatment, your doctor may go for frequent blood tests to check the proper liver and kidney functioning and measure your blood count, as jectophen 1.0gm injection can damage your blood cells, causing bone marrow suppression. Hence, you will be hospitalized until you recover. There is a risk of over-growth of non-susceptible organisms, which can lead to severe diarrhea up to a few months after this medicine is given to you. Inform your doctor if you face any side effects during or after the treatment. You must not take this medication as prophylaxis to prevent bacterial infections such as colds, influenza, or throat infections. This medication is for in-hospital use only provided by your doctor. Always inform your doctor if you have any concerns before taking this medication.

References

  1. Eramol (UK) Ltd, Electronic medicines compendium (EMC) , [Revised on Mar 2022], [Accessed on 23rd Sept 2023], https://www.medicines.org.uk/emc/product/12869/smpc
  2. Fresenius Kabi USA, LLC, US Food and Drug Administration (FDA), [Revised on Dec 2019], [Accessed on 23rd Sep 2023], https://fda.report/DailyMed/aed29594-211d-49ef-813f-131975a8d0e3
  3. Fusion Healthcare Pvt Ltd., [Revised on 2018] [Accessed on 19th Aug 2021], https://www.fusionhealthc.com/products/
  4. KD Tripathi, Essentials of Medical Pharmacology, Antimicrobialdrugs, 8th edition, 2019, 790-792
  5. Camille E. Beauduy, Lisa G. Winston, Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidinones, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 815-825.

Safety Advice

Pregnancy: unsafe Jectophen 1.0gm injection passes the placental barrier and can cause potentially toxic effects (grey baby syndrome) to the fetus. Hence, do not take this medication if you are pregnant, planning to get pregnant, or think you may get pregnant. Consult your doctor for more advice.

Lungs: Consult your doctor It is unknown whether jectophen 1.0gm injection is safe for persons suffering from lung disease. Inform your doctor if you have any lung disease before starting the treatment.

Breastfeeding: unsafe Due to the risk of developing grey baby syndrome, it is not recommended to take jectophen 1.0gm injections if you are breastfeeding. Seek a doctor's help for more advice.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS