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Jollimine 250mg Capsule

Salt Composition: PENICILLAMINE

₹165.00₹173.24

Inclusive of all taxes

Categories: Rheumatology

Conditions: Arthritis

Product Introduction

Jollimine 250mg capsule contains penicillamine as its active substance. It is a chelating agent that binds to certain metals in the body, including copper and lead, to facilitate their removal. It is used to treat Wilson's disease and lead poisoning. The medicine belongs to a group called DMARDs (disease-modifying antirheumatic drugs) and helps relieve pain and stiffness caused by rheumatoid arthritis in adults and children. It is also used to treat Still's disease in children. Jollimine 250mg capsule treats cystinuria, a kidney problem, in adults and children. It is also indicated for chronic active hepatitis, a type of liver disease, in adults.

Do not take this medicine if you are allergic to penicillamine or any other ingredient of this medicine. Do not take this medicine if you have previously experienced a reduction in WBC after taking this medicine. Do not take this medicine if you have ever had aplastic anaemia (severe reduction in blood cells), lupus erythematosus (an allergic condition that causes skin rashes), or kidney problems. Do not take this medicine if you have ever had thrombocytopenia (a blood disorder that causes bleeding into the skin, bruising, and more bleeding than usual after an injury).

Inform your doctor if you have protein in your urine, if you are pregnant or breastfeeding, if you have blood in your urine, if you have an active infection, or if you are an elderly patient. Your doctor will recommend complete blood and urine tests before starting treatment.

Uses

Relieve pain and stiffness caused by rheumatoid arthritis. Treats lead poisoning Treats Still’s disease in children Treats Wilson’s disease Treats cystinuria Chronic active hepatitis

How it works

As a chelating agent, Jollimine 250mg capsule chelates mercury, lead, copper, iron, and probably other heavy metals to form stable, soluble complexes that are readily excreted in the urine. In cystinuria, it lowers excess cystine excretion. It also inhibits the production of tropocollagen cross-links and cleaves them when newly created. The method of action in rheumatoid arthritis is uncertain; however, it appears to reduce disease activity.

How to Use

Take the medicine as prescribed by your doctor. Your doctor will decide the dose and duration of the treatment based on the disease condition and other factors. Swallow the capsules as a whole with a glass of water. Do not break, chew, crush, or dissolve the capsules. Take the capsules on an empty stomach.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Rash Diarrhea Epigastric pain, loss of appetite Loss of taste Nausea, mouth ulcer Vomiting Decreased bone marrow activity Protein in urine Serious Injection site reaction Inflammation of the pancreas Renal injury Liver problems Muscle weakness

Expert Tips

Unless it is almost time for the next dose, take it as soon as you remember, then just carry on as before. Do not take a double dose to make up for a forgotten tablet. Do not stop or change your treatment before talking to your doctor. Do not take Jollimine 250mg capsule if you are pregnant or breastfeeding. Your doctor may routinely take blood and urine tests to monitor the effectiveness of your treatment.

References

  1. Michael C. Byrns and Trevor M. Penning, Environmental Toxicology: Carcinogens and Heavy Metals, Goodman & Gilman’s The Pharmacological Basis of Therapeutics, 13th edition, 2018, 1297-1315.
  2. Gerard Laboratories, EMC, [Revised on October 2021] [Accessed on June 2023] https://www.medicines.org.uk/emc/product/2713/smpc

Safety Advice

Pregnancy: unsafe Jollimine 250mg capsule is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.

Lungs: Consult your doctor It is unknown whether Jollimine 250mg capsule can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Jollimine 250mg capsule because the medicine passes into the breast milk in small amounts and may harm your baby.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS